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产品信息
PA5-34662
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fragment corresponding to a region within amino acids 216 and 422 of UAP56 (Uniprot ID#Q13838)
偶联物
形式
Liquid
浓度
0.73 mg/mL
纯化类型
Antigen affinity chromatography
保存液
0.1M tris glycine, pH 7, with 10% glycerol
内含物
0.01% thimerosal
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2552014
产品详细信息
Recommended positive controls: HepG2.
Predicted reactivity: Mouse (100%), Rat (100%), Zebrafish (97%), Xenopus laevis (98%), Dog (100%), Pig (100%), Rhesus Monkey (100%), Chimpanzee (100%), Bovine (100%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
靶标信息
This gene encodes a member of the DEAD box family of RNA-dependent ATPases that mediate ATP hydrolysis during pre-mRNA splicing. The encoded protein is an essential splicing factor required for association of U2 small nuclear ribonucleoprotein with pre-mRNA, and also plays an important role in mRNA export from the nucleus to the cytoplasm. A cluster of genes, BAT1-BAT5, is localized in the vicinity of the genes for TNF alpha and TNF beta. These genes are all within the human major histocompatibility complex class III region. Mutations in this gene may be associated with rheumatoid arthritis. Alternatively spliced transcript variants encoding the same protein have been described.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: 56 kDa U2AF65-associated protein; ATP-dependent RNA helicase p47; DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B; DEAD box protein UAP56; HLA-B-associated transcript 1 protein; nuclear RNA helicase (DEAD family); spliceosome RNA helicase BAT1; Spliceosome RNA helicase DDX39B
基因别名: BAT1; D6S81E; DDX39B; UAP56
UniProt ID: (Human) Q13838
Entrez Gene ID: (Human) 7919
spliceosomal complex assembly
mRNA splicing, via spliceosome
liver development
termination of RNA polymerase II transcription
RNA export from nucleus
mRNA export from nucleus
RNA splicing
RNA secondary structure unwinding
mRNA 3'-end processing
positive regulation of DNA-templated transcription, elongation
positive regulation of translation
viral mRNA export from host cell nucleus
positive regulation of cell growth involved in cardiac muscle cell development
positive regulation of vascular smooth muscle cell proliferation
negative regulation of DNA damage checkpoint
positive regulation of DNA biosynthetic process
