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产品信息
MA5-15916
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Non-human primate
宿主/亚型
Mouse
/ IgG1
分类
Monoclonal
类型
Antibody
克隆号
1B10
抗原
Purified recombinant fragment of human UBE2I expressed in E. Coli.
偶联物
形式
Liquid
浓度
Conc. Not Determined
保存液
ascites
内含物
0.03% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_11152436
产品详细信息
MA5-15916 targets UBE2I in indirect ELISA, FACS, IF, IHC, and WB applications and shows reactivity with Human and Non-human primate samples.
The MA5-15916 immunogen is purified recombinant fragment of human UBE2I expressed in E. Coli. .
MA5-15916 detects UBE2I which has a predicted molecular weight of approximately 18kDa.
靶标信息
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. Four alternatively spliced transcript variants encoding the same protein have been found for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: mUBC9; OTTHUMP00000198131; p18; RING-type E3 SUMO transferase UBC9; SUMO-1-protein ligase; SUMO-conjugating enzyme UBC9; SUMO-protein ligase; Ubiquitin carrier protein 9; Ubiquitin carrier protein I; ubiquitin conjugating enzyme 9; ubiquitin conjugating enzyme E2I; Ubiquitin-conjugating enzyme E2 I; ubiquitin-conjugating enzyme E2I (homologous to yeast UBC9); ubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast); ubiquitin-conjugating enzyme UbcE2A; ubiquitin-like protein SUMO-1 conjugating enzyme; ubiquitin-protein ligase E2I; Ubiquitin-protein ligase I
基因别名: 5830467E05Rik; C358B7.1; F830028O17Rik; P18; UBC9; Ubce2i; UBCE9; UBE2I
UniProt ID: (Human) P63279, (Mouse) P63280
Entrez Gene ID: (Human) 7329, (Mouse) 22196
protein binding
ATP binding
transcription factor binding
ligase activity
SUMO transferase activity
enzyme binding
ubiquitin protein ligase binding
HLH domain binding
poly(A) RNA binding
ubiquitin protein ligase activity
SUMO conjugating enzyme activity
RING-like zinc finger domain binding
nucleotide binding
ubiquitin-protein transferase activity
protein C-terminus binding
UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity
ribosomal S6-glutamic acid ligase activity
bHLH transcription factor binding
coenzyme F420-0 gamma-glutamyl ligase activity
coenzyme F420-2 alpha-glutamyl ligase activity
protein-glycine ligase activity
protein-glycine ligase activity, initiating
protein-glycine ligase activity, elongating
tubulin-glycine ligase activity
protein-glutamic acid ligase activity
tubulin-glutamic acid ligase activity
negative regulation of transcription from RNA polymerase II promoter
cellular protein modification process
ubiquitin-dependent protein catabolic process
chromosome segregation
mitotic nuclear division
viral process
protein sumoylation
positive regulation of I-kappaB kinase/NF-kappaB signaling
negative regulation of transcription, DNA-templated
cell division
global genome nucleotide-excision repair
positive regulation of SUMO transferase activity
cell cycle
multicellular organism development
regulation of receptor activity
protein ubiquitination
positive regulation of intracellular steroid hormone receptor signaling pathway
proteasome-mediated ubiquitin-dependent protein catabolic process
positive regulation of sequence-specific DNA binding transcription factor activity
