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Positive control: THP-1 cell lysates, rat kidney tissue, human testis tissue, mouse cerebellum tissue.
Predicted band size: 112 kDa
Subcellular Location: Cytoplasm, cytosol, nucleoplasm, nucleus.
UBE1L (ubiquitin-like modifier-activating enzyme 7) activates ubiquitin by first adenylating with ATP at its C-terminal glycine residue and then linking that residue to the side chain of a cysteine residue in E1. This activation results in an ubiquitin-E1 thioester and free AMP. UBE1L also catalyzes the ISGylation of influenza A virus NS1 protein.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: D8; MGC12713; UBA1, ubiquitin-activating enzyme E1 homolog B; UBA7, ubiquitin-activating enzyme E1; Ubiquitin-activating enzyme 7; Ubiquitin-activating enzyme E1 homolog; ubiquitin-activating enzyme E1-related protein; ubiquitin-activating enzyme-2; ubiquitin-like modifier activating enzyme 7; Ubiquitin-like modifier-activating enzyme 7
基因别名: 1300004C08Rik; D8; UBA1B; UBA7; UBE1L; UBE2
UniProt ID: (Human) P41226, (Mouse) Q9DBK7
Entrez Gene ID: (Human) 7318, (Mouse) 74153, (Rat) 301000