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The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. UBE2J2 is a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is located in the membrane of the endoplasmic reticulum.The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is located in the membrane of the endoplasmic reticulum. Multiple alternatively spliced transcript variants have been found for this gene, but the full-length nature of some variants has not been defined.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: E2 ubiquitin-conjugating enzyme J2; NCUBE-2; Non-canonical ubiquitin-conjugating enzyme 2; ubiquitin conjugating enzyme 6; ubiquitin conjugating enzyme E2, J2; Ubiquitin-conjugating enzyme E2 J2; ubiquitin-conjugating enzyme E2, J2 (UBC6 homolog, yeast); ubiquitin-conjugating enzyme E2, J2 homolog; yeast UBC6 homolog
基因别名: NCUBE-2; NCUBE2; PRO2121; UBE2J2
UniProt ID: (Human) Q8N2K1
Entrez Gene ID: (Human) 118424, (Rat) 298689