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产品信息
PA1-9112
产品规格
种属反应
Human,
Mouse,
Pig,
Rat
宿主/亚型
Goat
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide corresponding to the C terminus amino acids EFTKKYGEKRPVD (aa 142-154).
偶联物
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Ammonium sulfate precipitation
保存液
TBS, pH 7.3, with 0.5% BSA
内含物
0.02% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
AB_2210906
产品详细信息
This antibody is predicted to react with bovine based on sequence homology.
This antibody is tested in Peptide ELISA: antibody detection limit dilution 128,000.
靶标信息
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes (E1s), ubiquitin-conjugating enzymes (E2s) and ubiquitin-protein ligases (E3s). UBE2L3 is a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is demonstrated to participate in the ubiquitination of p53, c-Fos, and the NF-kB precursor p105 in vitro.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: E2 ubiquitin-conjugating enzyme L3; L-UBC; UbcH7; UbcM4; Ubiquitin carrier protein L3; ubiquitin conjugating enzyme E2L 3; ubiquitin-conjugating enzyme 7; Ubiquitin-conjugating enzyme E2 L3; Ubiquitin-conjugating enzyme E2-F1; ubiquitin-conjugating enzyme E2L 3; ubiquitin-conjugating enzyme UBCH7; Ubiquitin-protein ligase L3
基因别名: C79827; E2-F1; L-UBC; UBCE7; UBCH7; UbcM4; UBE2L3
UniProt ID: (Human) P68036, (Mouse) P68037
Entrez Gene ID: (Pig) 100154268, (Human) 7332, (Rat) 363836, (Mouse) 22195
protein polyubiquitination
regulation of transcription, DNA-templated
metabolic process
cell proliferation
protein ubiquitination
positive regulation of protein ubiquitination
protein ubiquitination involved in ubiquitin-dependent protein catabolic process
cell cycle phase transition
positive regulation of ubiquitin-protein transferase activity
protein K11-linked ubiquitination
cellular response to steroid hormone stimulus
cellular response to glucocorticoid stimulus
transcription, DNA-templated
cellular protein modification process
ubiquitin-dependent protein catabolic process
positive regulation of protein targeting to mitochondrion
