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产品信息
PA5-21598
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Zebrafish
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide corresponding to a region within amino acids 92 and 154 of UBE2L3 (Uniprot ID#P68036)
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7, with 40% glycerol
内含物
0.01% thimerosal
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_11156402
产品详细信息
Recommended positive controls: HeLa, HepG2, Neuro2A, GL261, C8D30, mouse testis, whole zebrafish.
Predicted reactivity: Mouse (100%), Rat (100%), Xenopus laevis (100%), Pig (100%), Chicken (100%), Rhesus Monkey (100%), Bovine (100%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
靶标信息
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes (E1s), ubiquitin-conjugating enzymes (E2s) and ubiquitin-protein ligases (E3s). UBE2L3 is a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is demonstrated to participate in the ubiquitination of p53, c-Fos, and the NF-kB precursor p105 in vitro.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: E2 ubiquitin-conjugating enzyme L3; L-UBC; UbcH7; UbcM4; Ubiquitin carrier protein L3; ubiquitin conjugating enzyme E2L 3; ubiquitin-conjugating enzyme 7; Ubiquitin-conjugating enzyme E2 L3; Ubiquitin-conjugating enzyme E2-F1; ubiquitin-conjugating enzyme E2L 3; ubiquitin-conjugating enzyme UBCH7; Ubiquitin-protein ligase L3
基因别名: C79827; E2-F1; L-UBC; UBCE7; UBCH7; UbcM4; UBE2L3
UniProt ID: (Human) P68036, (Mouse) P68037
Entrez Gene ID: (Human) 7332, (Mouse) 22195
protein polyubiquitination
transcription, DNA-templated
regulation of transcription, DNA-templated
cellular protein modification process
ubiquitin-dependent protein catabolic process
cell proliferation
protein ubiquitination
positive regulation of protein ubiquitination
protein ubiquitination involved in ubiquitin-dependent protein catabolic process
cell cycle phase transition
positive regulation of ubiquitin-protein transferase activity
protein K11-linked ubiquitination
cellular response to steroid hormone stimulus
cellular response to glucocorticoid stimulus
positive regulation of protein targeting to mitochondrion
