Invitrogen

UBE2Z Polyclonal Antibody

UBE2Z Antibody in Immunocytochemistry (ICC/IF)

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UBE2Z Antibody (PA5-52486) in ICC/IF

Immunofluorecent analysis of UBE2Z in human cell line A-431 using UBE2Z Polyclonal Antibody (Product # PA5-52486). Staining shows localization to nucleoplasm and cytosol.

UBE2Z Antibody in Immunohistochemistry (Paraffin) (IHC (P))

UBE2Z Antibody in Immunohistochemistry (IHC)

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UBE2Z Antibody — Antibody specificity was demonstrated by siRNA mediated knockdown of target protein. U-138 mg were transfected with, control siRNA, UBE2Z siRNA (probe #1), and UBE2Z siRNA (probe #2) and a decrease in signal intensity was observed in Western Blot application using anti-UBE2Z Polyclonal Antibody (Product # PA5-52486) used at a dilution of 0.4 µg/mL. Anti-PPIB was used as a loading control. {KD}

产品信息

PA5-52486

应用

建议稀释比

已发表文章

免疫印迹 (WB)

0.04-0.4 µg/mL

免疫组化（石蜡） (IHC (P))

1:200-1:500

免疫细胞化学 (ICC/IF)

0.25-2 µg/mL

产品规格

种属反应

Human, Mouse, Rat

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

Recombinant protein corresponding to Human UBE2Z. Recombinant protein control fragment (Product #RP-89726).

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

0.1 mg/mL

纯化类型

Antigen affinity chromatography

保存液

PBS, pH 7.2, with 40% glycerol

内含物

0.02% sodium azide

保存条件

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

运输条件

Wet ice

AB_2649186

产品详细信息

Immunogen sequence: ISSVLISIQS LMTENPYHNE PGFEQERHPG DSKNYNECIR HETIRVAVCD MMEGKCPCPE PLRGVMEKSF LEYYDFYEVA CKDRLHLQGQ TMQDPFGEKR GHFDYQSLLM RLGLIRQKVL ERLHNENAEM DS

Highest antigen sequence identity to the following orthologs: Mouse - 100%, Rat - 100%.

靶标信息

This gene encodes an enzyme which ubiquitinates proteins which participate in signaling pathways and apoptosis.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

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引用该产品

生物信息学

蛋白别名: E2 ubiquitin-conjugating enzyme Z; Uba6-specific E2 conjugating enzyme 1; UBA6-specific enzyme E2; Ubiquitin carrier protein Z; ubiquitin conjugating enzyme E2Z; Ubiquitin-conjugating enzyme E2 Z; ubiquitin-conjugating enzyme E2Z; ubiquitin-conjugating enzyme E2Z (putative); Ubiquitin-protein ligase Z; Use1

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基因别名: AW049199; C030047H17Rik; D11Moh35; HOYS7; RGD1308347; UBE2Z; USE1

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UniProt ID: (Human) Q9H832, (Rat) Q3B7D1, (Mouse) Q3UE37

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Entrez Gene ID: (Human) 65264, (Rat) 303478, (Mouse) 268470

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功能

protein binding ATP binding ubiquitin protein ligase binding ubiquitin protein ligase activity ubiquitin conjugating enzyme activity ligase activity ubiquitin-like protein transferase activity nucleotide binding

参与通路

protein polyubiquitination apoptotic process protein ubiquitination protein ubiquitination involved in ubiquitin-dependent protein catabolic process