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产品信息
H00009690-D01P
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
UBE3C (AAH26241.1, 1 a.a. approximately 404 a.a) full-length human protein.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein A
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Product may be used with Western Blot (Transfected lysate).
The Isotype of this product is composed of an IgG Mixture.
Immunogen sequence: MFSFEGDFKT RPKVSLGGAS RKYSIQRSAF DRCATLSQSG GAFPIANGPN LTLLVRQLLF FYKQNEDSKR LIWLYQNLIK HSSLFVKQLD GSERLTCLFQ IKRLMSLCCR LLQNCNDDSL NVALPMRMLE VFSSENTYLP VLQDASYVVS VIEQILHYMI HNGYYRSLYL LINSKLPSSI EYSDLSRVPI AKILLENVLK PLHFTYNSCP EGARQQVFTA FTEEFLAAPF TDQIFHFIIP ALADAQTVFP YEPFLNALLL IESRCSRKSG GAPWLFYFVL TVGENYLGAL SEEGLLVYLR VLQTFLSQLP VSPASASCHD SASDSEEESE EADKPSSPED GRLSVSYITE ECLKKLDTKQ QTNTLLNLVW RDSASEEVFT TMASVCHTLM VQHRMMVPKV RVYK
靶标信息
E3 ubiquitin-protein ligase that accepts ubiquitin from the E2 ubiquitin-conjugating enzyme UBE2D1 in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Can assemble unanchored poly-ubiquitin chains in either 'Lys-29'- or 'Lys-48'-linked polyubiquitin chains. Has preference for 'Lys-48' linkages. It can target itself for ubiquitination in vitro and may promote its own degradation in vivo.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: HECT-type ubiquitin transferase E3C; HectH2; Homologous to E6AP carboxyl terminus homologous protein 2; RAUL; RTA-associated ubiquitin ligase; ubiquitin-protein isopeptide ligase (E3); Ubiquitin-protein ligase E3C
基因别名: HECTH2; KIAA0010; KIAA10; UBE3C
UniProt ID: (Human) Q15386
Entrez Gene ID: (Human) 9690
