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产品信息
PA5-142505
产品规格
种属反应
Human
宿主/亚型
Goat
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Peptide with sequence C-NTTRATSREEKNLQ.
偶联物
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Ammonium sulfate precipitation
保存液
TBS, pH 7.3, with 0.5% BSA
内含物
0.02% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
AB_2933152
产品详细信息
This antibody is tested in Peptide ELISA: antibody detection limit dilution 1:128,000.
靶标信息
E3 ubiquitin-protein ligase which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N-terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation. Together with clathrin, forms meshwork structures involved in membrane morphogenesis and cytoskeletal organization. Regulates integrin-mediated signaling. May play a role in activation of FAK in response to cell-matrix interactions. Mediates ubiquitination of ACLY, leading to its subsequent degradation.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: 600 kDa retinoblastoma protein-associated factor; E3 ubiquitin-protein ligase UBR4; N-recognin-4; p600; RBAF600; retinoblastoma-associated factor 600-like protein; Retinoblastoma-associated factor of 600 kDa; zinc finger UBR1-type protein 1
基因别名: KIAA0462; KIAA1307; p600; RBAF600; UBR4; ZUBR1
UniProt ID: (Human) Q5T4S7
Entrez Gene ID: (Human) 23352
