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UCP1 Antibody (MA5-31535) in IHC (P)
UCP1 Monoclonal Antibody (GT1345) detects UCP1 protein at cytoplasm by immunohistochemical analysis. Sample: Paraffin-embedded mouse brown adipocyte. UCP1 stained by UCP1 Monoclonal Antibody (GT1345) (Product # MA5-31535) diluted at 1:200. Antigen Retrieval: Citrate buffer, pH 6.0, 15 min.
产品信息
MA5-31535
产品规格
种属反应
Human,
Mouse
宿主/亚型
Mouse
/ IgG2a
分类
Monoclonal
类型
Antibody
克隆号
GT1345
抗原
Recombinant protein encompassing a sequence within the center region of human UCP1.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein A
保存液
PBS
内含物
no preservative
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2787163
产品详细信息
Keep as concentrated solution.
Predicted reactivity: Mouse (80%), Rat (80%), Rabbit (86%), Sheep (83%), Bovine (84%).
Positive Control: mouse brown adipose.
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
靶标信息
Mitochondrial uncoupling proteins are members of the family of mitochondrial anion carrier proteins. UCPs separate oxidative phosphorylation from ATP synthesis with energy dissipated as heat, also referred to as the mitochondrial proton leak. UCPs facilitate the transfer of anions from the inner to the outer mitochondrial membrane and the return transfer of protons from the outer to the inner mitochondrial membrane. They also reduce the mitochondrial membrane potential in mammalian cells. Tissue specificity occurs for the different UCPs and the exact methods of how UCPs transfer H+/OH- are not known. UCPs contain the three homologous protein domains of MACPs. This gene is expressed only in brown adipose tissue, a specialized tissue which functions to produce heat.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: HGNC:12517; Mitochondrial brown fat uncoupling protein 1; Solute carrier family 25 member 7; Thermogenin; UCP 1; uncoupling protein; uncoupling protein 1 (mitochondrial, proton carrier); uncoupling protein 1, mitochondrial; uncoupling protein, mitochondrial
基因别名: AI385626; SLC25A7; UCP; UCP1
UniProt ID: (Human) P25874, (Mouse) P12242
Entrez Gene ID: (Human) 7350, (Mouse) 22227
