Product References
Oxygen Consumption and Basal Metabolic Rate as Markers of Susceptibility to Malignant Hyperthermia and Heat Stroke.
Cells
Serano M,Pietrangelo L,Paolini C,Guarnier FA,Protasi F
PA1-055 was used in Western Blotting to suggest that metabolic rate, oxygen consumption, and body temperature at rest, all more elevated in Y522S than in CASQ1-null mice, could possibly be used as predictors of the level of susceptibility to hyperthermic crises of mice (and possibly humans).
Tue Aug 09 00:00:00 UTC 2022
Oxygen Consumption and Basal Metabolic Rate as Markers of Susceptibility to Malignant Hyperthermia and Heat Stroke.
Cells
Serano M,Pietrangelo L,Paolini C,Guarnier FA,Protasi F
PA1-055 was used in Western Blotting to suggest that metabolic rate, oxygen consumption, and body temperature at rest, all more elevated in Y522S than in CASQ1-null mice, could possibly be used as predictors of the level of susceptibility to hyperthermic crises of mice (and possibly humans).
Tue Aug 09 00:00:00 UTC 2022
Switching to a Standard Chow Diet at Weaning Improves the Effects of Maternal and Postnatal High-Fat and High-Sucrose Diet on Cardiometabolic Health in Adult Male Mouse Offspring.
Metabolites
Chiñas Merlin A,Gonzalez K,Mockler S,Perez Y,Jia UA,Chicco AJ,Ullevig SL,Chung E
PA1-055 was used in Protein Assay to test that switching to a standard chow diet after weaning would attenuate systemic metabolic disorders and cardiac and mitochondrial dysfunction associated with maternal and postnatal high-fat/high-sucrose (HFHS) diet in mice.
Sat Jun 18 00:00:00 UTC 2022
Nox4 mediates skeletal muscle metabolic responses to exercise.
Molecular metabolism
Specht KS,Kant S,Addington AK,McMillan RP,Hulver MW,Learnard H,Campbell M,Donnelly SR,Caliz AD,Pei Y,Reif MM,Bond JM,DeMarco A,Craige B,Keaney JF,Craige SM
PA1-055 was used in Western Blotting to demonstrate that endothelial-Nox4 is required for glucose and fatty acid oxidation, suggesting inter-tissue cross-talk between the endothelium and skeletal muscle in response to exercise.
Mon Mar 01 00:00:00 UTC 2021
Nox4 mediates skeletal muscle metabolic responses to exercise.
Molecular metabolism
Specht KS,Kant S,Addington AK,McMillan RP,Hulver MW,Learnard H,Campbell M,Donnelly SR,Caliz AD,Pei Y,Reif MM,Bond JM,DeMarco A,Craige B,Keaney JF,Craige SM
PA1-055 was used in Western Blotting to demonstrate that endothelial-Nox4 is required for glucose and fatty acid oxidation, suggesting inter-tissue cross-talk between the endothelium and skeletal muscle in response to exercise.
Mon Mar 01 00:00:00 UTC 2021
Cardiomyocyte-restricted high-mobility group box 1 (HMGB1) deletion leads to small heart and glycolipid metabolic disorder through GR/PGC-1α signalling.
Cell death discovery
Yu P,Liu M,Zhang B,Yu Y,Su E,Xie S,Zhang L,Yang X,Jiang H,Chen R,Zou Y,Ge J
PA1-055 was used in Western Blotting to find that HMGB1 deletion by cTnT-Cre in mouse hearts altered glucocorticoid receptor (GR) function and glycolipid metabolism, eventually leading to growth retardation, small heart and heart failure.
Wed Oct 28 00:00:00 UTC 2020
Cardiomyocyte-restricted high-mobility group box 1 (HMGB1) deletion leads to small heart and glycolipid metabolic disorder through GR/PGC-1α signalling.
Cell death discovery
Yu P,Liu M,Zhang B,Yu Y,Su E,Xie S,Zhang L,Yang X,Jiang H,Chen R,Zou Y,Ge J
PA1-055 was used in Western Blotting to find that HMGB1 deletion by cTnT-Cre in mouse hearts altered glucocorticoid receptor (GR) function and glycolipid metabolism, eventually leading to growth retardation, small heart and heart failure.
Wed Oct 28 00:00:00 UTC 2020
4-Hydroxynonenal induces Nrf2-mediated UCP3 upregulation in mouse cardiomyocytes.
Free radical biology & medicine
López-Bernardo E,Anedda A,Sánchez-Pérez P,Acosta-Iborra B,Cadenas S
PA1-055 was used in western blot to study the role of Nrf2 when mouse cardiomyocytes are treated with 4-Hydroxy-2-nonenal
Sun Nov 01 00:00:00 UTC 2015
Skeletal muscle dysfunction is associated with derangements in mitochondrial bioenergetics (but not UCP3) in a rodent model of sepsis.
American journal of physiology. Endocrinology and metabolism
Zolfaghari PS,Carré JE,Parker N,Curtin NA,Duchen MR,Singer M
PA1-055 was used in western blot to assess the metabolic, cardiovascular, and skeletal muscle contractile changes after induction of peritoneal sepsis in wild-type and Ucp3 knockout mice
Fri May 01 00:00:00 UTC 2015
Skeletal muscle dysfunction is associated with derangements in mitochondrial bioenergetics (but not UCP3) in a rodent model of sepsis.
American journal of physiology. Endocrinology and metabolism
Zolfaghari PS,Carré JE,Parker N,Curtin NA,Duchen MR,Singer M
PA1-055 was used in western blot to assess the metabolic, cardiovascular, and skeletal muscle contractile changes after induction of peritoneal sepsis in wild-type and Ucp3 knockout mice
Fri May 01 00:00:00 UTC 2015
Cardiac-specific adipose triglyceride lipase overexpression protects from cardiac steatosis and dilated cardiomyopathy following diet-induced obesity.
International journal of obesity (2005)
Pulinilkunnil T,Kienesberger PC,Nagendran J,Sharma N,Young ME,Dyck JR
PA1-055 was used in western blot to study the protective effects against cardiac steatosis and dilated cardiomyopathy of specifically overexpressing triglyceride lipase in cardiomyocytes in a murine model of diet-induced obesity
Sat Feb 01 00:00:00 UTC 2014
NF1 is a critical regulator of muscle development and metabolism.
Human molecular genetics
Sullivan K,El-Hoss J,Quinlan KG,Deo N,Garton F,Seto JT,Gdalevitch M,Turner N,Cooney GJ,Kolanczyk M,North KN,Little DG,Schindeler A
PA1-055 was used in western blot to study the role of NF1 in the development and metabolism of muscle
Sat Mar 01 00:00:00 UTC 2014
A novel SP1/SP3 dependent intronic enhancer governing transcription of the UCP3 gene in brown adipocytes.
PloS one
Hoffmann C,Zimmermann A,Hinney A,Volckmar AL,Jarrett HW,Fromme T,Klingenspor M
PA1-055 was used in western blot to study the regulation of brown adipocyte UCP3 transcription by a novel intronic enhancer that binds SP1 and SP3
Mon Aug 25 00:00:00 UTC 2014
Skeletal muscle respiratory capacity is enhanced in rats consuming an obesogenic Western diet.
American journal of physiology. Endocrinology and metabolism
Stephenson EJ,Camera DM,Jenkins TA,Kosari S,Lee JS,Hawley JA,Stepto NK
PA1-055 was used in Western Blotting to evaluate the effects of Western diet-induced obesity on skeletal muscle mitochondrial function.
Fri Jun 15 00:00:00 UTC 2012
Divergent skeletal muscle respiratory capacities in rats artificially selected for high and low running ability: a role for Nor1?
Journal of applied physiology (Bethesda, Md. : 1985)
Stephenson EJ,Stepto NK,Koch LG,Britton SL,Hawley JA
PA1-055 was used in western blot to study the potential role of Nor1 in the different metabolic profiles and capacities of rats with high and low running abilities
Thu Nov 01 00:00:00 UTC 2012
Dietary supplementation with vitamin E and C attenuates dexamethasone-induced glucose intolerance in rats.
American journal of physiology. Regulatory, integrative and comparative physiology
Williams DB,Wan Z,Frier BC,Bell RC,Field CJ,Wright DC
PA1-055 was used in western blot to study the effect of vitamin E and C on dexamethasone-induced glucose intolerance in rats
Sun Jan 01 00:00:00 UTC 2012
Exercise and PGC-1α-independent synchronization of type I muscle metabolism and vasculature by ERRγ.
Cell metabolism
Narkar VA,Fan W,Downes M,Yu RT,Jonker JW,Alaynick WA,Banayo E,Karunasiri MS,Lorca S,Evans RM
PA1-055 was used in western blot to investigate the role of ERR gamma in coordinating type I muscle metabolism and vascular transformation in muscles
Wed Mar 02 00:00:00 UTC 2011
PGC-1β deficiency accelerates the transition to heart failure in pressure overload hypertrophy.
Circulation research
Riehle C,Wende AR,Zaha VG,Pires KM,Wayment B,Olsen C,Bugger H,Buchanan J,Wang X,Moreira AB,Doenst T,Medina-Gomez G,Litwin SE,Lelliott CJ,Vidal-Puig A,Abel ED
Published figure using UCP3 polyclonal antibody (Product # PA1-055) in Western Blot
Fri Sep 16 00:00:00 UTC 2011
Amelioration of lipid-induced insulin resistance in rat skeletal muscle by overexpression of Pgc-1β involves reductions in long-chain acyl-CoA levels and oxidative stress.
Diabetologia
Wright LE,Brandon AE,Hoy AJ,Forsberg GB,Lelliott CJ,Reznick J,Löfgren L,Oscarsson J,Strömstedt M,Cooney GJ,Turner N
PA1-055 was used in western blot to investigate the ameliorative effect of Ppargc1b expression in insulin resistance in rat skeletal muscle
Wed Jun 01 00:00:00 UTC 2011
PPARδ agonists have opposing effects on insulin resistance in high fat-fed rats and mice due to different metabolic responses in muscle.
British journal of pharmacology
Ye JM,Tid-Ang J,Turner N,Zeng XY,Li HY,Cooney GJ,Wulff EM,Sauerberg P,Kraegen EW
PA1-055 was used in western blot to investigate the different effect of PPARdelta agonist on diabetic treatment between rats and mice
Wed Jun 01 00:00:00 UTC 2011
Effect of LKB1 deficiency on mitochondrial content, fibre type and muscle performance in the mouse diaphragm.
Acta physiologica (Oxford, England)
Brown JD,Hancock CR,Mongillo AD,Benjamin Barton J,DiGiovanni RA,Parcell AC,Winder WW,Thomson DM
PA1-055 was used in western blot to investigate the role of LKB1 in skeletal muscle metabolic processes
Fri Apr 01 00:00:00 UTC 2011
Exercise training reverses impaired skeletal muscle metabolism induced by artificial selection for low aerobic capacity.
American journal of physiology. Regulatory, integrative and comparative physiology
Lessard SJ,Rivas DA,Stephenson EJ,Yaspelkis BB,Koch LG,Britton SL,Hawley JA
PA1-055 was used in western blot to investigate the effect of exercise on the treatment of muscle impairment
Sat Jan 01 00:00:00 UTC 2011
Transforming growth factor β₁ oppositely regulates the hypertrophic and contractile response to β-adrenergic stimulation in the heart.
PloS one
Huntgeburth M,Tiemann K,Shahverdyan R,Schlüter KD,Schreckenberg R,Gross ML,Mödersheim S,Caglayan E,Müller-Ehmsen J,Ghanem A,Vantler M,Zimmermann WH,Böhm M,Rosenkranz S
PA1-055 was used in western blot to investigate the role of TGF-beta 1 in heart response to beta-epinephrine
Mon Apr 02 00:00:00 UTC 2012
Loss of bradykinin signaling does not accelerate the development of cardiac dysfunction in type 1 diabetic akita mice.
Endocrinology
Wende AR,Soto J,Olsen CD,Pires KM,Schell JC,Larrieu-Lahargue F,Litwin SE,Kakoki M,Takahashi N,Smithies O,Abel ED
PA1-055 was used in western blot to investigate the involvement of bradykinin signaling in diabetic cardiomyopathy
Sun Aug 01 00:00:00 UTC 2010
Chronic AMP-activated protein kinase activation and a high-fat diet have an additive effect on mitochondria in rat skeletal muscle.
Journal of applied physiology (Bethesda, Md. : 1985)
Fillmore N,Jacobs DL,Mills DB,Winder WW,Hancock CR
PA1-055 was used in western blot to study the effect of chronic AMPK activation and high-fat diet on mitochondria in rat skeletal muscle
Sun Aug 01 00:00:00 UTC 2010
GDP and carboxyatractylate inhibit 4-hydroxynonenal-activated proton conductance to differing degrees in mitochondria from skeletal muscle and heart.
Biochimica et biophysica acta
Aguirre E,Cadenas S
PA1-055 was used in western blot to investigate the differences of proton conductance mechanism between skeletal muscle and heart
Fri Oct 01 00:00:00 UTC 2010
AMP-activated protein kinase response to contractions and treatment with the AMPK activator AICAR in young adult and old skeletal muscle.
The Journal of physiology
Thomson DM,Brown JD,Fillmore N,Ellsworth SK,Jacobs DL,Winder WW,Fick CA,Gordon SE
PA1-055 was used in western blot to investigate the influence of AICAR or muscle contraction on AMPK activity in old and young adult rat muscles
Fri May 01 00:00:00 UTC 2009
Impaired skeletal muscle beta-adrenergic activation and lipolysis are associated with whole-body insulin resistance in rats bred for low intrinsic exercise capacity.
Endocrinology
Lessard SJ,Rivas DA,Chen ZP,van Denderen BJ,Watt MJ,Koch LG,Britton SL,Kemp BE,Hawley JA
PA1-055 was used in western blot to investigate the effect of beta-adrenergic signal transduction on metabolic health
Sun Nov 01 00:00:00 UTC 2009
c-Cbl-deficient mice have reduced adiposity, higher energy expenditure, and improved peripheral insulin action.
The Journal of clinical investigation
Molero JC,Jensen TE,Withers PC,Couzens M,Herzog H,Thien CB,Langdon WY,Walder K,Murphy MA,Bowtell DD,James DE,Cooney GJ
PA1-055 was used in western blot to study the role of casitas b-lineage lymphoma (c-Cbl) in the whole-body fuel homeostasis.
Mon Nov 01 00:00:00 UTC 2004
Expression of mitochondrial uncoupling protein 3 and adenine nucleotide translocase 1 genes in developing rat heart: putative involvement in control of mitochondrial membrane potential.
Journal of molecular and cellular cardiology
Skárka L,Bardová K,Brauner P,Flachs P,Jarkovská D,Kopecký J,Ostádal B
PA1-055 was used in western blot to investigate the expression of mitochondrial uncoupling protein 3 and adenine nucleotide translocase 1 genes in rat heart during development and its role in mitochondrial membrane potential
Sat Mar 01 00:00:00 UTC 2003
