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产品信息
H00054659-M02
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG2b, kappa
分类
Monoclonal
类型
Antibody
克隆号
1C10
抗原
UGT1A3 (NP_061966, 30 a.a. approximately 129 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
偶联物
形式
Liquid
浓度
0.5-1 mg/mL
纯化类型
Protein A
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Product may be used with Sandwich ELISA (Recombinant protein).
Immunogen sequence: KVLVVPIDGS HWLSMREVLR ELHARGHQAV VLTPEVNMHI KEENFFTLTT YAISWTQDEF DRHVLGHTQL YFETEHFLKK FFRSMAMLNN MSLVYHRSCV
靶标信息
UDP-glucuronosyltransferase 1-3 is an enzyme that in humans is encoded by the UGT1A3 gene. This gene encodes a UDP-glucuronosyltransferase, an enzyme of the glucuronidation pathway that transforms small lipophilic molecules, such as steroids, bilirubin, hormones, and drugs, into water-soluble, excretable metabolites. This gene is part of a complex locus that encodes several UDP-glucuronosyltransferases. The locus includes thirteen unique alternate first exons followed by four common exons. Four of the alternate first exons are considered pseudogenes. Each of the remaining nine 5' exons may be spliced to the four common exons, resulting in nine proteins with different N-termini and identical C-termini. Each first exon encodes the substrate binding site, and is regulated by its own promoter. Substrates of this enzyme include estrone, 2-hydroxyestrone, and metabolites of benzo alpha-pyrene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: GNT1; polypeptide A3; UDP glucuronosyltransferase 1 family; UDP glucuronosyltransferase 1 family, polypeptide A3; UDP glycosyltransferase 1 family, polypeptide A3; UDP-glucuronosyltransferase 1 family polypeptide A3s; UDP-glucuronosyltransferase 1-3; UDP-glucuronosyltransferase 1-C; UDP-glucuronosyltransferase 1A isoform 3; UDP-glucuronosyltransferase 1A3; UDPGT 1-3; UGT-1C; UGT1; UGT1*3; UGT1A3
基因别名: GNT1; UDPGT; UDPGT 1-3; UGT-1C; UGT1; UGT1-03; UGT1.3; UGT1A3; UGT1A3S; UGT1C
UniProt ID: (Human) P35503
Entrez Gene ID: (Human) 54659
