Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
图: 1 / 1
UHMK1 Antibody (PA5-50622) in WB
Frontiers in oncology 2022 -
LncRNA H19-induced UHMK1 is highly expressed in PDAC. (A) Volcano plot showing differentially expressed genes in MIA-PaCa2 cell line depleted for lncRNA H19 using the siRNAs siH19-1 (left panel) and siRNAs siH19-2 (right panel), in comparison with cells transfected with a nonsense siRNA control (NC). The threshold was set to a log 2 (fold change) >1 and a P value <0.05. Vertical axis corresponds to the stat... View More
产品信息
PA5-50622
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
已发表种属
Not Applicable
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide corresponding to residues near the C terminal of human U2AF homology motif (UHM) kinase 1
偶联物
形式
Liquid
浓度
1.7 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.4, with 40% glycerol
内含物
0.05% sodium azide
保存条件
-20°C
运输条件
Wet ice
RRID
AB_2636075
产品详细信息
The antibody detects endogenous levels of total UHMK1 protein.
靶标信息
Upon serum stimulation, KIS, a member of the Ser/Thr protein kinase family, phosphorylates CDKN1B/p27Kip1, thus controlling CDKN1B subcellular location and cell cycle progression in G1 phase. This protein, which contains 1 RRM (RNA recognition motif)domain, may be involved in trafficking and/or processing of RNA. KIS is widely expressed, with highest levels in skeletal muscle, kidney, placenta and peripheral blood leukocytes.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: kinase interacting stathmin; kinase interacting with leukemia-associated gene (stathmin); Kinase interacting with stathmin; KIS protein kinase; P-CIP2; PAM COOH-terminal interactor protein 2; Serine/threonine-protein kinase Kist; U2AF homology motif kinase 1
基因别名: 4732477C12Rik; 4930500M09Rik; AA673513; AI449218; AU021979; KIS; KIST; P-CIP2; UHMK1
UniProt ID: (Human) Q8TAS1, (Mouse) P97343, (Rat) Q63285
Entrez Gene ID: (Human) 127933, (Mouse) 16589, (Rat) 246332
mRNA binding
protein serine/threonine kinase activity
protein binding
ATP binding
transferase activity
ribonucleoprotein complex binding
nucleotide binding
nucleic acid binding
RNA binding
protein kinase activity
kinase activity
transferase activity, transferring phosphorus-containing groups
enzyme binding
non-receptor serine/threonine protein kinase
protein modifying enzyme
nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
regulation of alternative mRNA splicing, via spliceosome
cell cycle arrest
peptidyl-serine phosphorylation
neuron projection development
positive regulation of translational initiation
protein autophosphorylation
regulation of protein export from nucleus
protein phosphorylation
phosphorylation
