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产品信息
PA5-110548
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 1-290 of human ULK4 (NP_060356.2).
偶联物
形式
Liquid
浓度
0.33 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
AB_2855959
产品详细信息
Immunogen sequence: MENFILYEEI GRGSKTVVYK GRRKGTINFV AILCTDKCKR PEITNWVRLT REIKHKNIVT FHEWYETSNH LWLVVELCTG GSLKTVIAQD ENLPEDVVRE FGIDLISGLH HLHKLGILFC DISPRKILLE GPGTLKFSNF CLAKVEGENL EEFFALVAAE EGGGDNGENV LKKSMKSRVK GSPVYTAPEV VRGADFSISS DLWSLGCLLY EMFSGKPPFF SESISELTEK ILCEDPLPPI PKDSSRPKAS SDFINLLDGL LQRDPQKRLT WTRLLQHSFW KKAFAGADQE
靶标信息
The phosphorylation and dephosphorylation of proteins on serine and threonine residues is an essential means of regulating a broad range of cellular functions in eukaryotes, including cell division, homeostasis and apoptosis. A group of proteins that are intimately involved in this process are the serine/threonine (Ser/Thr) protein kinases. ULK4 (unc-51-like kinase 4) is a 1,275 amino acid protein that contains one protein kinase domain and one HEAT repeat and belongs to the Ser/Thr protein kinase family. Although containing what is thought to be a catalytically inactive domain, ULK4 may play a role in the ATP-dependent phosphorylation of target proteins.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Serine/threonine-protein kinase ULK4; unc-51 like kinase 4; Unc-51-like kinase 4
基因别名: 4932415A06Rik; A730098P15; FAM7C1; REC01035; RGD1565726; ULK4
UniProt ID: (Human) Q96C45, (Mouse) Q3V129
Entrez Gene ID: (Human) 54986, (Mouse) 209012, (Rat) 363167
microtubule cytoskeleton organization
protein phosphorylation
regulation of neuron projection development
regulation of MAPK cascade
regulation of JNK cascade
regulation of protein kinase C signaling
regulation of p38MAPK cascade
regulation of neuron migration
epithelial cilium movement
phosphorylation
ventricular system development
corpus callosum development
cilium morphogenesis
biological_process
