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USH1C Antibody (PA5-115341) in ICC/IF
Immunocytochemistry analysis of USH1C in HepG2 cells. Samples were treated with PFA, permeabilized in 0.1% Triton X-100, blocked in 10% serum (45 min at 25°C), and incubated with polyclonal antibody (Product # PA5-115341). Secondary staining was applied with mouse anti-beta tubulin (1 hr at 37°, AlexaFluor 594 conjugated goat anti-rabbit IgG (Red), AlexaFluor 488 conjugated goat anti-mouse IgG (Green) and DAPI.
产品信息
PA5-115341
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human USH1C(Accession Q9Y6N9), corresponding to amino acid residues Q406-L456.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Affinity chromatography
保存液
PBS with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice
RRID
AB_2899977
产品详细信息
Antibody detects endogenous levels of total Harmonin.
靶标信息
This gene encodes a scaffold protein that functions in the assembly of Usher protein complexes. The protein contains PDZ domains, a coiled-coil region with a bipartite nuclear localization signal and a PEST degradation sequence. Defects in this gene are the cause of Usher syndrome type 1C and non-syndromic sensorineural deafness autosomal recessive type 18. Multiple transcript variants encoding different isoforms have been found for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Antigen NY-CO-38/NY-CO-37; Autoimmune enteropathy-related antigen AIE-75; Harmonin; harmonin a1; PDZ domain-containing protein; PDZ-73 protein; Protein PDZ-73; Renal carcinoma antigen NY-REN-3; Usher syndrome 1C (autosomal recessive, severe); Usher syndrome 1C homolog; Usher syndrome type-1C protein; Usher syndrome type-1C protein homolog
基因别名: 2010016F01Rik; AIE-75; AIE75; DFNB18; DFNB18A; harmonin; NY-CO-37; NY-CO-38; PDZ-45; PDZ-73; PDZ-73/NY-CO-38; PDZ73; PDZD7C; USH1C; ush1cpst
UniProt ID: (Human) Q9Y6N9, (Mouse) Q9ES64
Entrez Gene ID: (Human) 10083, (Rat) 308596, (Mouse) 72088
G2/M transition of mitotic cell cycle
sensory perception of sound
cell differentiation
regulation of microvillus length
cellular protein complex assembly
photoreceptor cell maintenance
sensory perception of light stimulus
equilibrioception
protein localization to microvillus
brush border assembly
parallel actin filament bundle assembly
inner ear morphogenesis
auditory receptor cell differentiation
neuromuscular process controlling balance
actin filament bundle assembly
inner ear receptor stereocilium organization
