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USP21 Antibody (PA5-116440) in IHC (P)
Immunohistochemical analysis of USP21 in a paraffin-embedded human fetal skeletal muscle tissue using a USP21 polyclonal antibody (Product #PA5-116440). The section was pre-treated using heat mediated antigen retrieval with Tris-EDTA buffer (pH 8.0-8.4) for 20 minutes. The tissues were blocked in 5% BSA for 30 minutes at room temperature, washed with ddH2O and PBS, and then probed with the primary antibody ... View More
产品信息
PA5-116440
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant protein within Human USP21 aa 303-453
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.4, with 50% glycerol, 0.2% BSA
内含物
0.05% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2901072
产品详细信息
Positive controls: SHSY5Y cell lysates, Rat kidney tissue, human fetal skeletal muscle tissue, Mouse heart tissue, SHSY5Y.
靶标信息
This gene encodes a member of the C19 peptidase family, also known as family 2 of ubiquitin carboxy-terminal hydrolases. The encoded protein cleaves ubiquitin from ubiquitinated proteins for recycling in intracellular protein degradation. The encoded protein is also able to release NEDD8, a ubiquitin-like protein, from NEDD8-conjugated proteins. This gene has been referred to as USP16 and USP23 but is now known as USP21. Alternatively spliced transcript variants have been described.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Deubiquitinating enzyme 21; NEDD8-specific protease; Ubiquitin carboxyl-terminal hydrolase 21; ubiquitin specific protease 21; ubiquitin specific protease 23; Ubiquitin thioesterase 21; ubiquitin thiolesterase 21; ubiquitin-specific processing protease 21; ubiquitin-specific protease 16; ubiquitin-specific protease 21; Ubiquitin-specific-processing protease 21
基因别名: ESTM28; PP1490; USP16; USP21; USP23; W53272
UniProt ID: (Human) Q9UK80, (Mouse) Q9QZL6, (Rat) B2GUX4
Entrez Gene ID: (Human) 27005, (Mouse) 30941, (Rat) 688466
transcription coactivator activity
thiol-dependent ubiquitin-specific protease activity
protein binding
cysteine-type peptidase activity
NEDD8-specific protease activity
metal ion binding
cysteine-type endopeptidase activity
peptidase activity
hydrolase activity
thiol-dependent ubiquitinyl hydrolase activity
molecular_function
cysteine protease
transcription, DNA-templated
ubiquitin-dependent protein catabolic process
histone deubiquitination
neuron projection development
positive regulation of transcription, DNA-templated
regulation of transcription, DNA-templated
proteolysis
chromatin modification
proteasome-mediated ubiquitin-dependent protein catabolic process
regulation of proteasomal protein catabolic process
