Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
图: 1 / 1
USP22 Antibody (PA5-110557) in WB
Western blot analysis of USP22 in extracts of various cell lines. Samples were incubated with USP22 Polyclonal antibody (Product # PA5-110557) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 5 min.
产品信息
PA5-110557
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthetic peptide corresponding to a sequence within amino acids 50-150 of human USP22 (NP_0560911)
偶联物
形式
Liquid
浓度
0.41 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.01% thimerosal
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
AB_2855968
产品详细信息
Immunogen sequence: TAEARKRKAK SCICHVCGVH LNRLHSCLYC VFFGCFTKKH IHEHAKAKRH NLAIDLMYGG IYCFLCQDYI YDKDMEIIAK EEQRKAWKMQ GVGEKFSTWE P
靶标信息
Histone deubiquitinating component of the transcription regulatory histone acetylation (HAT) complex SAGA. Catalyzes the deubiquitination of both histones H2A and H2B, thereby acting as a coactivator. Recruited to specific gene promoters by activators such as MYC, where it is required for transcription. Required for nuclear receptor-mediated transactivation and cell cycle progression.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
篇参考文献 (0)
您是否在文献中引用过该产品？请点击下方按钮邮件告知我们。
生物信息学
蛋白别名: Deubiquitinating enzyme 22; Ubiquitin carboxyl-terminal hydrolase 22; ubiquitin specific protease 22; Ubiquitin thioesterase 22; ubiquitin thiolesterase 22; ubiquitin-specific processing protease 22; Ubiquitin-specific-processing protease 22
基因别名: AI427806; KIAA1063; USP22; USP3L
UniProt ID: (Human) Q9UPT9, (Mouse) Q5DU02
Entrez Gene ID: (Human) 23326, (Mouse) 216825
transcription coactivator activity
thiol-dependent ubiquitin-specific protease activity
protein binding
zinc ion binding
H4 histone acetyltransferase activity
enzyme binding
ligand-dependent nuclear receptor transcription coactivator activity
cysteine-type endopeptidase activity
peptidase activity
cysteine-type peptidase activity
hydrolase activity
thiol-dependent ubiquitinyl hydrolase activity
metal ion binding
cysteine protease
transcription, DNA-templated
ubiquitin-dependent protein catabolic process
cell cycle
embryo development
histone ubiquitination
histone deubiquitination
protein deubiquitination
histone H4 acetylation
positive regulation of transcription, DNA-templated
positive regulation of mitotic cell cycle
regulation of transcription, DNA-templated
proteolysis
chromatin modification
proteasome-mediated ubiquitin-dependent protein catabolic process
regulation of proteasomal protein catabolic process
