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Product Details
PA5-116665
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 290-400 of human USP33 (NP_9639201)
Conjugate
Form
Liquid
Concentration
0.93 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.01% thimerosal
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
RRID
AB_2901296
Product Specific Information
Positive Samples: HeLa, HepG2
Immunogen sequence: QVMEVEEDPQ TITTEETMEE DKSQSDVDFQ SCESCSNSDR AENENGSRCF SEDNNETTML IQDDENNSEM SKDWQKEKMC NKINKVNSEG EFDKDRDSIS ETVDLNNQET V
Target Information
DNA-directed RNA polymerase I subunit RPA43 or Twist neighbor protein (Twistnb)belongs to the eukaryotic RPA43 RNA polymerase subunit family. It catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.Twistnb is the component of RNA polymerase I which synthesizes ribosomal RNA precursors. It is widely expressed in all fetal and adult tissues, with highest expression in fetal lung, liver, and kidney, and low expression in all adult tissues. Twist genes are essential for embryonic development and are conserved from jellyfish to human.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Deubiquitinating enzyme 33; hVDU1; pVHL-interacting deubiquitinating enzyme 1; Ubiquitin carboxyl-terminal hydrolase 33; ubiquitin specific protease 33; Ubiquitin thioesterase 33; ubiquitin thiolesterase 33; Ubiquitin-specific-processing protease 33; VHL-interacting deubiquitinating enzyme 1; Vhlh-interacting deubiquitinating enzyme 1
Gene Aliases: 9830169D19Rik; AA409780; KIAA1097; USP33; VDU1
UniProt ID: (Human) Q8TEY7, (Mouse) Q8R5K2
Entrez Gene ID: (Human) 23032, (Mouse) 170822, (Rat) 310960
G-protein coupled receptor binding
cysteine-type endopeptidase activity
thiol-dependent ubiquitin-specific protease activity
protein binding
zinc ion binding
Ral GTPase binding
ubiquitin binding
peptidase activity
cysteine-type peptidase activity
hydrolase activity
thiol-dependent ubiquitinyl hydrolase activity
metal ion binding
cysteine protease
ubiquitin-dependent protein catabolic process
endocytosis
axon guidance
regulation of G-protein coupled receptor protein signaling pathway
cellular response to starvation
regulation of autophagy
cell migration
protein deubiquitination
negative regulation of protein binding
positive regulation of protein binding
protein stabilization
centrosome duplication
protein K63-linked deubiquitination
protein K48-linked deubiquitination
proteolysis
proteasome-mediated ubiquitin-dependent protein catabolic process
regulation of proteasomal protein catabolic process
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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