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USP47 Antibody (IHC-00235) in IHC (P)
Detection of human USP47 by immunohistochemistry. Sample: FFPE section of human prostate adenocarcinoma. Antibody: Affinity purified rabbit anti-USP47 (Product # IHC-00235) used at a dilution of 1:100. Detection: Red-fluorescent Alexa Fluor® 555 goat anti-rabbit IgG (Invitrogen) used at a dilution of 1:500.
产品信息
IHC-00235
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Region between residue 1237 and the C-terminus (residue 1287) of Human ubiquitin specific peptidase 47.
偶联物
形式
Liquid
浓度
0.25 mg/mL
纯化类型
Antigen affinity chromatography
保存液
TBS, pH 7.0 to 8.0, with 0.1% BSA
内含物
0.09% sodium azide
保存条件
4° C
运输条件
Wet ice
产品详细信息
The recommended shelf life for this product is 1 year from date of receipt.
Based on 100% sequence identity, this antibody is predicted to react with Chicken, Turkey, Bovine, Dog, Rabbit, Pig, Panda, Orangutan, Monkey, Gorilla, Chimpanzee and Naked mole rat
靶标信息
Ubiquitin-specific protease that specifically deubiquitinates monoubiquitinated DNA polymerase beta (POLB), stabilizing POLB thereby playing a role in base-excision repair (BER). Acts as a regulator of cell growth and genome integrity. May also indirectly regulate CDC25A expression at a transcriptional level. [UniProt]
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Deubiquitinating enzyme 47; Trf (TATA binding protein-related factor)-proximal homolog; Ubiquitin carboxyl-terminal hydrolase 47; ubiquitin specific protease 47; Ubiquitin thioesterase 47; ubiquitin thiolesterase 47; Ubiquitin-specific-processing protease 47
基因别名: 4930502N04Rik; A630020C16Rik; TRFP; USP47
UniProt ID: (Human) Q96K76, (Mouse) Q8BY87
Entrez Gene ID: (Human) 55031, (Mouse) 74996
base-excision repair
ubiquitin-dependent protein catabolic process
cellular response to DNA damage stimulus
negative regulation of G2/M transition of mitotic cell cycle
positive regulation of cell growth
cellular response to UV
monoubiquitinated protein deubiquitination
response to drug
negative regulation of apoptotic process
negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
negative regulation of transcription, DNA-templated
negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage
DNA repair
proteolysis
protein deubiquitination
proteasome-mediated ubiquitin-dependent protein catabolic process
regulation of proteasomal protein catabolic process
