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Recommended positive controls: 293T, A431, Jurkat.
Predicted reactivity: Mouse (94%), Rat (93%), Chicken (84%), Rhesus Monkey (99%), Bovine (97%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Acts as a GTPase-activating protein for RAB5A and RAB43. Involved in receptor trafficking. In complex with EPS8 inhibits internalization of EGFR. Involved in retrograde transport from the endocytic pathway to the Golgi apparatus. Involved in the transport of Shiga toxin from early and recycling endosomes to the trans-Golgi network. Required for structural integrity of the Golgi complex. [UniProt]
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Related to the N-terminus of tre; RN-tre; USP6 N-terminal-like protein
基因别名: KIAA0019; RNTRE; TRE2NL; USP6NL; USP6NL-IT1
UniProt ID: (Human) Q92738
Entrez Gene ID: (Human) 9712