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The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Acts as a GTPase-activating protein for RAB5A and RAB43. Involved in receptor trafficking. In complex with EPS8 inhibits internalization of EGFR. Involved in retrograde transport from the endocytic pathway to the Golgi apparatus. Involved in the transport of Shiga toxin from early and recycling endosomes to the trans-Golgi network. Required for structural integrity of the Golgi complex. [UniProt]
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: novel TBC domain containing protein; Related to the N-terminus of tre; RN-tre; USP6 N-terminal-like protein
基因别名: AI316785; KIAA0019; mKIAA0019; RNTRE; TRE2NL; USP6NL; USP6NL-IT1
UniProt ID: (Human) Q92738, (Mouse) Q80XC3
Entrez Gene ID: (Human) 9712, (Rat) 291309, (Mouse) 98910