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产品信息
PA5-76626
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant full length Human UTS2.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 50% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2720353
产品详细信息
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
靶标信息
Urotensin II is an active cyclic heptapeptide absolutely conserved from lamprey to human. The active peptide acts as a vasoconstrictor and is expressed only in brain tissue. Despite the gene family name similarity, this gene is not homologous to urocortin, a member of the sauvagine/corticotropin releasing factor/urotensin I family. Most of the proprotein is cleaved to make the mature peptide.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: prepro U-II; U-II; urocortin 2; Urotensin II; Urotensin-2; urotensin-II
基因别名: prepro-UII; PRO1068; U-II; UCN2; UII; UNQ525/PRO1068; UTS2
UniProt ID: (Human) O95399, (Mouse) Q9QZQ3
Entrez Gene ID: (Human) 10911, (Mouse) 24111
response to hypoxia
negative regulation of glomerular filtration
muscle contraction
positive regulation of cytosolic calcium ion concentration
chemical synaptic transmission
regulation of blood pressure
negative regulation of heart rate
positive regulation of heart rate
positive regulation of fibroblast migration
positive regulation of circadian sleep/wake cycle, wakefulness
positive regulation of synaptic transmission, cholinergic
positive regulation of collagen biosynthetic process
response to testosterone
negative regulation of urine volume
negative regulation of renal sodium excretion
response to drug
positive regulation of cell differentiation
positive regulation of angiogenesis
negative regulation of blood pressure
positive regulation of blood pressure
positive regulation of vasodilation
positive regulation of circadian sleep/wake cycle, REM sleep
negative regulation of insulin secretion
positive regulation of fibroblast proliferation
regulation of vasodilation
