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Positive test controls include: HeLa, HeLa+MG132, NIH/3T3, C6, Mouse brain, Rat brain.
Ubiquitin is a conserved 76 amino acid polypeptide and can affect proteasomal degradation of the protein it is bound to, or mediate interactions with other proteins related to post-translational modifications. The degradation of cellular regulatory proteins by the Uubiquitin pathway is important as it controls the cellular growth and proliferation. Ubiquitin-dependent proteolysis occurs after a covalent attachment of the peptide to a lysine residue of a protein, which involves three enzymatic reactions: E1, E2 and E3. The first reaction involves ubiquitin-activating enzyme. The third reaction uses enzyme ubiquitin ligase (E3) to transfer the activated ubiquitin from E2 to a lysine residue on a protein, or directly transfers the ubiquitin from E2 to the substrate.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: 40S ribosomal protein S27a; 60S ribosomal protein L40; CEP52; epididymis luminal protein 112; epididymis secretory protein Li 50; polyubiquitin B; polyubiquitin C; Polyubiquitin-B; Polyubiquitin-C; Ubiquitin A-52 residue ribosomal protein fusion product 1; ubiquitin and ribosomal protein S27a; ubiquitin C; ubiquitin carboxyl extension protein 52; Ubiquitin carboxyl extension protein 80; ubiquitin-40S ribosomal protein S27a; ubiquitin-40S ribosomal protein S27a-like; ubiquitin-52 amino acid fusion protein; ubiquitin-60S ribosomal protein L40; ubiquitin-CEP52; ubiquitin-CEP80; Ubiquitin-ribosomal protein eL40 fusion protein; Ubiquitin-ribosomal protein eS31 fusion protein; ubiquitin/60S ribosomal fusion protein
基因别名: 0610006J14Rik; 2700054O04Rik; AI194771; AL033289; CEP52; CEP80; D8Ertd21e; Gm1863; HEL-S-50; HEL112; HMG20; HUBCEP52; L40; RPL40; RPS27A; S27A; TI-225; UBA52; UBA80; UBB; Ubb2; UBC; UBCEP1; UBCEP2; UBCEP80
UniProt ID: (Rat) P62982, (Human) P62979, (Mouse) P62983, (Human) P62987, (Human) P0CG47, (Human) P0CG48, (Mouse) P62984, (Rat) P62986, (Mouse) P0CG49, (Rat) P0CG51, (Mouse) Q29120, (Rat) Q63429
Entrez Gene ID: (Rat) 100912032, (Human) 6233, (Mouse) 78294, (Human) 7311, (Human) 7314, (Human) 7316, (Mouse) 22186, (Rat) 64156, (Mouse) 22187, (Rat) 192255, (Mouse) 22190, (Rat) 50522