Invitrogen

Ubinuclein 1 Polyclonal Antibody

Ubinuclein 1 Antibody in Immunocytochemistry (ICC/IF)

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Ubinuclein 1 Antibody (PA5-103360) in ICC/IF

Immunocytochemistry analysis of Ubinuclein 1 in Hela cells. The samples were fixed with PFA and permeabilized in 0.1% Triton X-100, then blocked in 10% serum for 45 minutes at 25°C. Samples were incubated with Ubinuclein 1 polyclonal antibody (Product # PA5-103360) and mouse anti-beta tubulin antibody for 1 hour at 37°C. An AlexaFluor594 conjugated goat anti-rabbit IgG (Red) and an AlexaFluor488 conjugated ... View More

Ubinuclein 1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

Ubinuclein 1 Antibody in Western Blot (WB)

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产品信息

PA5-103360

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:1,000-1:3,000

免疫组化（石蜡） (IHC (P))

1:50-1:200

免疫细胞化学 (ICC/IF)

1:100-1:500

产品规格

种属反应

Human, Mouse

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

A synthesized peptide derived from human UBN1(Accession Q9NPG3), corresponding to amino acid residues Q303-L353.

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

1 mg/mL

纯化类型

Affinity chromatography

保存液

PBS, pH 7.4, with 50% glycerol

内含物

0.02% sodium azide

保存条件

-20°C

运输条件

Wet ice

AB_2852704

产品详细信息

Antibody detects endogenous levels of total Ubinuclein.

靶标信息

Cellular senescence is a hallmark of tumor suppression and tissue aging. Senescent cells contain domains of heterochromatin, called senescence-associated heterochromatin foci (SAHF), that repress proliferation-promoting genes. The protein encoded by this gene binds to proliferation-promoting genes and is required for SAHF formation, enhancing methylation of histone H3.

仅用于科研。不用于诊断过程。未经明确授权不得转售。