Search Thermo Fisher Scientific
Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.
Specificity of this antibody: VAMP4.
The vesicle associated membrane proteins (VAMP) or synaptobrevins are calcium binding proteins specific to eukaryotes. VAMPs, along with synaptosomal associated protein of 25 kDa (SNAP-25) and syntaxin, form the core complex of soluble NSF attachment protein receptor (SNARE) proteins that interact with the soluble proteins N-ethylmaleimide-sensitive factor (NSF) and alpha-SNAP. These membrane associated proteins play a key role in the regulation of vesicle membrane fusion with the plasma membrane. The Clostridium tetani neurotoxin is a metalloprotease with specificity for VAMP. In Alzheimer’s disease, VAMP levels of all isoforms appear to be significantly lowered.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: vamp; VAMP-4; vesicle associated membrane protein 4; Vesicle-associated membrane protein 4
基因别名: D1Ertd147e; VAMP-4; VAMP24; VAMP4
UniProt ID: (Human) O75379, (Mouse) O70480
Entrez Gene ID: (Human) 8674, (Mouse) 53330, (Rat) 364033