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VAPB Antibody (MA5-24348) in IHC (P)
Immunohistochemical analysis of VAPB in immersion fixed paraffin-embedded sections of human brain (medulla). Samples were incubated in VAPB monoclonal antibody (Product # MA5-24348) using a dilution of 15 µg/mL overnight at 4 °C. Before incubation with the primary antibody, tissue was subjected to heat-induced epitope retrieval using Antigen Retrieval Reagent-Basic . Tissue was stained using the Anti-Mouse ... View More
产品信息
MA5-24348
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
已发表种属
Not Applicable
宿主/亚型
Mouse
/ IgG1
分类
Monoclonal
类型
Antibody
克隆号
736904
抗原
E. coli-derived recombinant human VAP-B Ala2-Pro132
偶联物
形式
Lyophilized
浓度
0.5 mg/mL
纯化类型
Protein A/G
保存液
PBS with 5% trehalose
内含物
No Preservative
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2609923
产品详细信息
Reconstitute in sterile PBS to a final concentration of 0.5 mg/mL.
靶标信息
Vesicle-associated membrane protein-associated protein B/C is a protein that in humans is encoded by the VAPB gene. The VAPB gene is found on the 20th human chromosome. The protein encoded by this gene is a type IV membrane protein found in plasma and intracellular vesicle membranes. The encoded protein is found as a homodimer and as a heterodimer with VAPA. This protein also can interact with VAMP1 and VAMP2 and may be involved in vesicle trafficking.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: ALS 8; ALS8VAMP-B/VAMP-C; vamp; VAMP (vesicle-associated membrane protein)-associated protein B and C; Vamp 33b; VAMP B; VAMP B VAMP C; VAMP B/VAMP C; VAMP C; VAMP-associated 33 kDa protein; VAMP-B/VAMP-C; VAMP-C; VAMPB; VAMPB/VAMPC; VAMPC; VAP 33b; VAP B; VAP B/VAP C; VAP C; VAP-B/VAP-C; VAP-C; VAPB/VAPC; VAPC; Vesicle-associated membrane protein-associated protein B/C
基因别名: ALS8; UNQ484/PRO983; VAMP-B; VAP-B; VAPB
UniProt ID: (Human) O95292
Entrez Gene ID: (Human) 9217
cellular calcium ion homeostasis
ER to Golgi vesicle-mediated transport
activation of signaling protein activity involved in unfolded protein response
endoplasmic reticulum organization
modulation by virus of host morphology or physiology
sphingolipid biosynthetic process
endoplasmic reticulum unfolded protein response
positive regulation of viral genome replication
COPII-coated vesicle budding
cell-cell adhesion
