Invitrogen

VAV3 Polyclonal Antibody

VAV3 Antibody in Immunocytochemistry (ICC/IF)

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VAV3 Antibody (PA5-90428) in ICC/IF

Immunofluorescence analysis of VAV3 in L929 cells. Samples were incubated with VAV3 Polyclonal antibody (Product # PA5-90428) using a dilution of 1:100. Blue: DAPI for nuclear staining.

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产品信息

PA5-90428

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:200-1:2,000

免疫细胞化学 (ICC/IF)

1:50-1:200

酶联免疫吸附实验 (ELISA)

1 µg/mL

产品规格

种属反应

Human, Mouse

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

Recombinant fusion protein containing a sequence corresponding to amino acids 560-680 of human VAV3 (NP_0061044)

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

0.9 mg/mL

纯化类型

Affinity Chromatography

保存液

PBS, pH 7.3, with 50% glycerol

内含物

0.01% thimerosal

保存条件

-20° C, Avoid Freeze/Thaw Cycles

运输条件

Wet ice

AB_2806069

产品详细信息

Immunogen sequence: DNCGRVNSGE QGTLKLPEKR TNGLRRTPKQ VDPGLPKMQV IRNYSGTPPP ALHEGPPLQL QAGDTVELLK GDAHSLFWQG RNLASGEVGF FPSDAVKPCP CVPKPVDYSC QPWYAGAMER L; Positive Samples: Jurkat, Mouse brain, Mouse lung, Mouse spleen

靶标信息

This gene is a member of the VAV gene family. The VAV proteins are guanine nucleotide exchange factors (GEFs) for Rho family GTPases that activate pathways leading to actin cytoskeletal rearrangements and transcriptional alterations. This gene product acts as a GEF preferentially for RhoG, RhoA, and to a lesser extent, RAC1, and it associates maximally with the nucleotide-free states of these GTPases. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.

仅用于科研。不用于诊断过程。未经明确授权不得转售。