Invitrogen

VAV3 Recombinant Rabbit Monoclonal Antibody (9A10D8)

VAV3 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

图: 1 / 2

VAV3 Antibody (MA5-42927) in IHC (P)

Immunohistochemistry analysis of VAV3 in paraffin-embedded human esophageal cancer. Samples were incubated with VAV3 Monoclonal antibody (Product # MA5-42927) using a dilution of 1:100 (40x lens). Perform microwave antigen retrieval with 10 mM Tris/EDTA buffer pH 9.0 before commencing with IHC staining protocol.

Product Image Gallery

产品信息

MA5-42927

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:100-1:500

免疫组化（石蜡） (IHC (P))

1:50-1:200

酶联免疫吸附实验 (ELISA)

1 µg/mL

产品规格

种属反应

Human, Mouse

宿主/亚型

Rabbit / IgG

Expression System

HEK293 cells

分类

Recombinant Monoclonal

类型

Antibody

克隆号

9A10D8

抗原

A synthetic peptide corresponding to a sequence within amino acids 700-800 of human VAV3 (Q9UKW4).

查看免疫原

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

0.66 mg/mL

纯化类型

Affinity Chromatography

保存液

PBS, pH 7.3, with 0.05% BSA, 50% glycerol

内含物

0.02% sodium azide

保存条件

-20° C, Avoid Freeze/Thaw Cycles

运输条件

Ambient (domestic); Wet ice (international)

AB_2912068

产品详细信息

Positive test controls include: Jurkat, Mouse brain.

Immunogen sequence: TKESGEYAIS IKYNNEAKHI KILTRDGFFH IAENRKFKSL MELVEYYKHH SLKEGFRTLD TTLQFPYKEP EHSAGQRGNR AGNSLLSPKV LGIAIARYDF C

靶标信息

This gene is a member of the VAV gene family. The VAV proteins are guanine nucleotide exchange factors (GEFs) for Rho family GTPases that activate pathways leading to actin cytoskeletal rearrangements and transcriptional alterations. This gene product acts as a GEF preferentially for RhoG, RhoA, and to a lesser extent, RAC1, and it associates maximally with the nucleotide-free states of these GTPases. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

仅用于科研。不用于诊断过程。未经明确授权不得转售。