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VCAM-1 Antibody (MA1-10065) in Flow
Separation of HDLM-2 cells stained using anti-CD106 (STA) purified Monoclonal antibody (Product # MA1-10065) (concentration in sample 1.7 µg/mL, GAM APC, red-filled) from HDLM-2 cells unstained by primary antibody (GAM APC, black-dashed) in flow cytometry analysis (sufrace staining).
产品信息
MA1-10065
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG1
分类
Monoclonal
类型
Antibody
克隆号
STA
抗原
Human DS6 T cell line
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein A
保存液
PBS, pH 7.4
内含物
15mM sodium azide
保存条件
4° C, do not freeze
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_11152561
产品详细信息
This antibody recognizes an extracellular epitope of CD106 antigen (VCAM-1), a 100-110 kDa type I membrane protein of the immunoglobulin superfamily, a crucial mediator of leukocyte adhesion, and a costimulation molecule.
Immunohistochemistry (Frozen): acetone fixation.
靶标信息
VCAM-1 is a cell surface sialoglycoprotein expressed by cytokine activated endothelium. The protein has a number of functions including the regulation of leukocyte migration, leukocyte-endothelial cell adhesion and signal transduction and may play a role in a number of inflammatory diseases.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: CD106; CD106 antigen; DKFZp779G2333; INCAM-100; INCAM100; MGC99561; sCD106; soluble CD106; soluble VCAM 1; sVCAM 1; V-CAM 1; Vascular cell adhesion protein 1
基因别名: CD106; INCAM-100; VCAM1
UniProt ID: (Human) P19320
Entrez Gene ID: (Human) 7412
response to hypoxia
acute inflammatory response
chronic inflammatory response
cell adhesion
heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules
leukocyte cell-cell adhesion
cell-matrix adhesion
aging
response to nutrient
amine metabolic process
response to zinc ion
response to ionizing radiation
viral process
membrane to membrane docking
B cell differentiation
extracellular matrix organization
response to lipopolysaccharide
response to nicotine
calcium-mediated signaling using intracellular calcium source
cellular response to vascular endothelial growth factor stimulus
positive regulation of T cell proliferation
response to ethanol
regulation of immune response
leukocyte tethering or rolling
oxidation-reduction process
cell chemotaxis
interferon-gamma-mediated signaling pathway
cellular response to tumor necrosis factor
