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产品信息
PA5-34459
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A 19 amino acid synthetic peptide near the carboxy terminus of human VNN3
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS
内含物
0.02% sodium azide
保存条件
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2551811
产品详细信息
A suggested positive control is human brain tissue lysate.
PA5-34459 can be used with blocking peptide PEP-1501.
靶标信息
The vanin family is a novel group of ectoenzymes that function in tissue repair and plays a role in oxidative-stress response. As both secreted and membrane proteins, the vanin family members have been implicated as therapeutic targets in inflammatory disease. VNN3 (vascular non-inflammatory molecule 3), also known as Vanin3, is a 501 amino acid GPI-anchored amidohydrolase that is widely expressed and is found at highest levels in blood and liver. Induced by Th17 / Th1 type cytokines, VNN3 converts pantetheine into pantothenic acid. Containing one CN hydrolase domain, VNN3 is encoded by a gene that maps to human chromosome 6q23.2.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: pantetheinase pseudogene; pantetheinase-associated gene expressed in leukocytes (PAGEL)-alpha; vanin 1 pseudogene; Vanin-3; Vascular non-inflammatory molecule 3
基因别名: HSA238982; RGD1560609; Vnn3
UniProt ID: (Mouse) Q9QZ25
Entrez Gene ID: (Human) 55350, (Rat) 498992, (Mouse) 26464
