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VPAC1 (VIPR1) (extracellular) Antibody (AVR-001-200UL) in ICC/IF
Expression of VPAC1 in human HT-29 cells - Cell surface detection of VPAC1 in live intact human HT-29 colorectal adenocarcinoma cells. A. Extracellular staining of live cells with Anti-VPAC1 (VIPR1) (extracellular) Antibody (#AVR-001), (1:25), followed by goat Anti-rabbit-AlexaFluor-594 secondary Antibody (red). B. Cell nuclei were visualized using Hoechst 33342 (blue). C. Live view of the cells.
产品信息
AVR-001-200UL
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
(C)EEAQLENETIG(S)SK, corresponding to amino acid residues 52-65 of human VPAC1, Extracellular, N-terminus
偶联物
形式
Lyophilized
浓度
0.8 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.4, with 1% BSA
内含物
0.05% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Reconstitution: 25 µL, 50 µL or 0.2 mL double distilled water (DDW), depending on the sample size. The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20C. The reconstituted solution can be stored at 4C for up to 1 week. For longer periods, small aliquots should be stored at -20C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).
靶标信息
The Vasoactive Intestinal Polypeptide Receptor 1 (VPAC1) is a member of a family of three G-protein coupled receptors which mediate VIP (vasoactive intestinal peptide) and PACAP (pituitary adenlyate cyclase activating peptide) function in a variety of tissues. Together, the VPAC1 and VPAC2 receptors compose a subtype of the VIP receptor. Expression of the VIP and PACAP receptors has been linked to the presence of human tumors.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Pacap receptor; PACAP type II receptor; PACAP-R-2; PACAP-R2; pituitary adenylate cyclase activating polypeptide receptor, type II; Pituitary adenylate cyclase-activating polypeptide type II receptor; Pvr2; type 1 vasoactive intestinal peptide receptor; Vasoactive intestinal polypeptide receptor 1; Vasopressive intestinal peptide receptor; VIP and PACAP receptor 1; VIP receptor 1; VIP receptor subtype 1; VIP receptor, type I; VIP-R-1; VIP1 receptor; VPAC1; VPAC1 receptor
基因别名: AV071699; HVR1; II; PACAP-R-2; PACAP-R2; RATVASREC; RDC1; V1RG; VAPC1; VASREC; VIP-R-1; VIP-R1; VIPR; VIPR1; VIRG; VPAC1; VPAC1R; VPCAP1R
UniProt ID: (Human) P32241, (Rat) P30083, (Mouse) P97751
Entrez Gene ID: (Human) 7433, (Rat) 24875, (Mouse) 22354
muscle contraction
immune response
cell surface receptor signaling pathway
G-protein coupled receptor signaling pathway
G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger
chemical synaptic transmission
digestion
positive regulation of cell proliferation
signal transduction
