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Antibody detects endogenous levels of total VPS33B.
Vesicle mediated protein sorting plays an important role in segregation of intracellular molecules into distinct organelles. Genetic studies in yeast have identified more than 40 vacuolar protein sorting (VPS) genes involved in vesicle transport to vacuoles. This gene is a member of the Sec-1 domain family, and encodes the human ortholog of rat Vps33b which is homologous to the yeast class C Vps33 protein. The mammalian class C Vps proteins are predominantly associated with late endosomes/lysosomes, and like their yeast counterparts, may mediate vesicle trafficking steps in the endosome/lysosome pathway.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: FLJ14848; hVPS33B; r-vps33b; vacuolar protein sorting 33 homolog B; vacuolar protein sorting 33-like protein B; vacuolar protein sorting 33B; vacuolar protein sorting homolog r-vps33b; Vacuolar protein sorting-associated protein 33B; vacuolar sorting protein 33b; vps33b
基因别名: VPS33B; zgc:110803
UniProt ID: (Human) Q9H267, (Mouse) P59016, (Rat) Q63616, (Zebrafish) Q58EN8
Entrez Gene ID: (Human) 26276, (Mouse) 233405, (Rat) 64060, (Zebrafish) 541534