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产品信息
PA5-76288
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein of human VPS37A.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 50% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2720015
产品详细信息
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
靶标信息
This gene belongs to the VPS37 family, and encodes a component of the ESCRT-I (endosomal sorting complex required for transport I) protein complex, required for the sorting of ubiquitinated transmembrane proteins into internal vesicles of multivesicular bodies. Expression of this gene is downregulated in hepatocellular carcinoma, and mutations in this gene are associated with autosomal recessive spastic paraplegia-53. A related pseudogene has been identified on chromosome 5. Alternatively spliced transcript variants have been found for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: ESCRT-I complex subunit VPS37A; Hepatocellular carcinoma-related protein 1; hVps37A; polyglutamine binding protein 2; vacuolar protein sorting 37 homolog A; vacuolar protein sorting 37A; Vacuolar protein sorting-associated protein 37A; Vps37A
基因别名: 2210018P21Rik; 4930592A21Rik; AW261445; D8Ertd531e; HCRP1; PQBP2; SPG53; VPS37A
UniProt ID: (Human) Q8NEZ2, (Mouse) Q8CHS8
Entrez Gene ID: (Human) 137492, (Mouse) 52348, (Rat) 290775
