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产品信息
PA5-100365
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human VPS39(Accession Q96JC1), corresponding to amino acid residues E410-I460.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice
RRID
AB_2849878
产品详细信息
Antibody detects endogenous levels of total VPS39.
靶标信息
VPS39 is the mammalian homolog of the yeast vacuolar protein VAM6, that in mammals, promotes lysosome clustering and fusion in vivo. VPS39 is also thought to modulate the TGF-beta response by coupling the TGF-beta receptor complex to the Smad pathway. Similar to the related protein TRAP1, the VPS39 protein is essential for early embryonic development, with mice lacking VPS39 dying at or before E6. 5.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: hVam6p; OTTMUSP00000023341; OTTMUSP00000023350; PI3K type 3; TRAP1-like protein; vacuolar protein sorting 39 homolog; Vam6/Vps39-like protein; VPS39 HOPS complex subunit
基因别名: A230065P22Rik; AW743070; hVam6p; KIAA0770; mVam6; Pldn; TLP; VAM6; Vam6P; VPS39
UniProt ID: (Human) Q96JC1, (Mouse) Q8R5L3
Entrez Gene ID: (Human) 23339, (Mouse) 269338
