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产品信息
PA5-57855
产品规格
种属反应
Human
已发表种属
Not Applicable
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
偶联物
形式
Liquid
浓度
0.2 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2649480
产品详细信息
Immunogen sequence: EEIYPYIRTL LHFDTREFLN VLALTFEDFK NDKQAVEYQQ RIVDILLKVM VENSDFTPSQ VGCLFTFLAR QLA
Highest antigen sequence identity to the following orthologs: Mouse - 97%, Rat - 97%.
靶标信息
Plays a role in vesicle-mediated protein trafficking of the endocytic membrane transport pathway. Believed to act as a component of the putative CORVET endosomal tethering complexes which is proposed to be involved in the Rab5-to-Rab7 endosome conversion probably implicating MON1A/B, and via binding SNAREs and SNARE complexes to mediate tethering and docking events during SNARE-mediated membrane fusion. The CORVET complex is proposed to function as a Rab5 effector to mediate early endosome fusion probably in specific endosome subpopulations (PubMed:25266290). Functions predominantly in APPL1-containing endosomes (PubMed:25266290). [UniProt]
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: vacuolar protein sorting 8 homolog; Vacuolar protein sorting-associated protein 8 homolog; VPS8 CORVET complex subunit
基因别名: KIAA0804; VPS8
UniProt ID: (Human) Q8N3P4
Entrez Gene ID: (Human) 23355
