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VTI1A Antibody (PA5-101956) in IHC (P)
Immunohistochemistry analysis of VTI1A in human ovarian cancer. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. Samples were incubated with VTI1A polyclonal antibody (Product # PA5-101956) using a dilution of 1:100 (4°C overnight) followed by HRP conjugated anti-Rabbit secondary antibody.
产品信息
PA5-101956
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human VTI1A(Accession Q96AJ9), corresponding to amino acid residues K34-L84.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice
RRID
AB_2851388
产品详细信息
Antibody detects endogenous levels of total VTI1A.
靶标信息
V-SNARE that mediates vesicle transport pathways through interactions with t-SNAREs on the target membrane. These interactions are proposed to mediate aspects of the specificity of vesicle trafficking and to promote fusion of the lipid bilayers. Involved in vesicular transport from the late endosomes to the trans-Golgi network. Along with VAMP7, involved in an non- conventional RAB1-dependent traffic route to the cell surface used by KCNIP1 and KCND2. May be involved in increased cytokine secretion associated with cellular senescence.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: SNARE Vti1a-beta protein; vesicle transport through interaction with t-SNAREs 1 homolog; Vesicle transport through interaction with t-SNAREs homolog 1A; Vesicle transport v-SNARE protein Vti1-like 2; Vti1-rp2
基因别名: 1110014F16Rik; 1110018K19Rik; 4921537J05Rik; MMDS3; MVti1; MVti1a; Vti1; Vti1-rp2; VTI1A; Vti1l2; VTI1RP2
UniProt ID: (Human) Q96AJ9, (Mouse) O89116, (Rat) Q9JI51
Entrez Gene ID: (Human) 143187, (Mouse) 53611, (Rat) 65277
protein targeting to vacuole
ER to Golgi vesicle-mediated transport
intra-Golgi vesicle-mediated transport
Golgi to vacuole transport
autophagy
retrograde transport, endosome to Golgi
vesicle fusion with Golgi apparatus
voluntary musculoskeletal movement
Golgi ribbon formation
transport
intracellular protein transport
protein transport
vesicle-mediated transport
membrane fusion
