Invitrogen

Villin Monoclonal Antibody (CWWB1)

Villin Antibody in Immunohistochemistry (Paraffin) (IHC (P))

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Villin Antibody (MA5-12227) in IHC (P)

Formalin-fixed, paraffin-embedded human kidney stained with Villin antibody using peroxidase-conjugate and AEC chromogen. Note brush border and cytoplasmic staining of epithelial cells in the proximal tubules.

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产品信息

MA5-12227

应用

建议稀释比

已发表文章

免疫印迹 (WB)

2 µg/mL

免疫组化 (IHC)

查看3篇已发表文章 3篇已发表文章

免疫组化（石蜡） (IHC (P))

1:50-1:100

查看2篇已发表文章 2篇已发表文章

产品规格

种属反应

Human, Mouse

已发表种属

Human, Mouse, Rat

宿主/亚型

Mouse / IgG1

分类

Monoclonal

类型

Antibody

克隆号

CWWB1

抗原

Human Villin protein

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

0.2 mg/mL

纯化类型

Protein G

保存液

PBS, pH 7.4, with 0.2% BSA

内含物

0.09% sodium azide

保存条件

4° C

运输条件

Ambient (domestic); Wet ice (international)

AB_10980388

产品详细信息

MA5-12227 targets Villin in IHC (P) applications and shows reactivity with Human samples.

The MA5-12227 immunogen is human Villin protein.

靶标信息

Villin is part of cytoskeleton associated with the microvillar actin core bundle of gastrointestinal and renal brush border. It can interact with actin in a Ca2+ and phosphoinositide-regulated manner. Villin is a very specific marker for adenocarcinomas of the gastrointestinal tract and the pancreas. It is also expressed in some Merkel cell tumor and adenocarcinoma of the lung, prostate, ovarian and kidney.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

Product References

NPC1L1-dependent transport of 27-alkyne cholesterol in intestinal epithelial cells.

American journal of physiology. Cell physiology

Ticho AL,Calzadilla N,Malhotra P,Lee H,Anbazhagan AN,Saksena S,Dudeja PK,Lee D,Gill RK,Alrefai WA

MA5-12227 was used in Immunohistochemistry to show that alkyne cholesterol acts as a substrate for NPC1L1 and may serve as a nonradioactive tracer to measure cholesterol absorption in both in vitro and in vivo models.

Sat May 01 00:00:00 UTC 2021

Oncogenic transformation of diverse gastrointestinal tissues in primary organoid culture.

Nature medicine

Li X,Nadauld L,Ootani A,Corney DC,Pai RK,Gevaert O,Cantrell MA,Rack PG,Neal JT,Chan CW,Yeung T,Gong X,Yuan J,Wilhelmy J,Robine S,Attardi LD,Plevritis SK,Hung KE,Chen CZ,Ji HP,Kuo CJ

MA5-12227 was used in immunohistochemistry - paraffin section to study the oncogenic transformation in primary organoid culture of gastrointestinal tissues

Tue Jul 01 00:00:00 UTC 2014

Pulmonary enteric adenocarcinoma: a study of the clinicopathologic and molecular status of nine cases.

International journal of clinical and experimental pathology

Wang CX,Liu B,Wang YF,Zhang RS,Yu B,Lu ZF,Shi QL,Zhou XJ

MA5-12227 was used in immunohistochemistry to report on nine cases of pulmonary enteric adenocarcinoma

Fri Dec 19 00:00:00 UTC 2014

Efficient differentiation of human embryonic stem cells to definitive endoderm.

Nature biotechnology

D'Amour KA,Agulnick AD,Eliazer S,Kelly OG,Kroon E,Baetge EE

MA5-12227 was used in immunohistochemistry - paraffin section to elucidate the differentiation of human embryonic stem cells to definitive endoderm efficiently

Thu Dec 01 00:00:00 UTC 2005

Phenotype of columnar-lined esophagus in rats with esophagogastroduodenal anastomosis: similarity to human Barrett's esophagus.

Laboratory investigation; a journal of technical methods and pathology

Su Y,Chen X,Klein M,Fang M,Wang S,Yang CS,Goyal RK

MA5-12227 was used in Immunohistochemistry to describe the morphology and phenotypic features of columnar-lined oesophagus and oesophageal adenocarcinoma in the rat model and compares them with the corresponding lesions in human Barrett's esophagus.