Invitrogen

Vitronectin Monoclonal Antibody (347317)

Vitronectin Antibody in Immunohistochemistry (Frozen) (IHC (F))

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Vitronectin Antibody (MA5-24083) in IHC (F)

Immunohistochemical analysis of Vitronectin was detected in immersion fixed frozen sections of fetal mouse brain using 10 µg/mL Rat Anti-mouse Vitronectin Monoclonal Antibody (Product # MA5-24083) overnight at 4 °C. Tissue was stained with a 557-conjugated Anti-Rat IgG Secondary Antibody (re and counterstained with DAPI (blue).

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产品信息

MA5-24083

应用

建议稀释比

已发表文章

免疫组化 (IHC)

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免疫组化（冰冻） (IHC (F))

8-25 µg/mL

产品规格

种属反应

Mouse

已发表种属

Mouse

宿主/亚型

Rat / IgG2a

分类

Monoclonal

类型

Antibody

克隆号

347317

抗原

Mouse myeloma cell line NS0-derived recombinant mouse Vitronectin Asp20-Lys478

查看免疫原

偶联物

Unconjugated Unconjugated Unconjugated

形式

Lyophilized

浓度

0.5 mg/mL

纯化类型

Protein A/G

保存液

PBS with 5% trehalose

内含物

No Preservative

保存条件

-20° C, Avoid Freeze/Thaw Cycles

运输条件

Ambient (domestic); Wet ice (international)

AB_2609020

产品详细信息

In direct ELISAs, no cross-reactivity with recombinant human Vitronectin is observed.

Reconstitute at 0.5 mg/mL in sterile PBS.

靶标信息

VTN is a member of the pexin family. This protein is found in serum and tissues and promotes cell adhesion and spreading, inhibits the membrane-damaging effect of the terminal cytolytic complement pathway, and binds to several serpin serine protease inhibitors. The protein is a secreted protein and exists in either a single chain form or a clipped, two chain form held together by a disulfide bond.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

Product References

Single-cell analysis of salt-induced hypertensive mouse aortae reveals cellular heterogeneity and state changes.

Experimental & molecular medicine

Zhang K,Kan H,Mao A,Geng L,Ma X

MA5-24083 was used in Immunohistochemistry-immunofluorescence to illustrate the transcriptional landscape of vascular cells in the aorta associated with hypertension and reveal dramatic changes in cell composition and intercellular communication during the progression of hypertension.

Wed Dec 01 00:00:00 UTC 2021

Siah2 integrates mitogenic and extracellular matrix signals linking neuronal progenitor ciliogenesis with germinal zone occupancy.

Nature communications

Ong T,Trivedi N,Wakefield R,Frase S,Solecki DJ

MA5-24083 was used in Immunohistochemistry-immunofluorescence to show ubiquitin ligase Siah2 E3 controls cerebellar granule neurons by linking responses to Shh mitogen and the extracellular matrix.