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Immunogen sequence: DLFTWPGQRE RSFHPEQDAG KVFKGHRNQV TCLSVSTDGS VLLSGSHDET VRLWDVQSKQ CIRTVALKGP VTNAAILLAP VSMLSSDFRP SLPLPHFNKH LLGAEHGDEP RHGGLTLRLG LHQQGSEPSY LDRTEQLQAV LCSTMEKSVL GGQDQLRVRV TELEDEVRNL RKINRDLFDF STRFITRPAK
WD repeat domain 18 (WDR18) is a member of the WD repeat protein family, which is involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. WD repeats are minimally conserved regions of approximately 40 amino acids that commonly form a tertiary propeller structure. WDR18 is a 432 amino acid protein that contains six WD repeats and is encoded by a gene located on human chromosome 19. WDR18 may play a role during development. The complex PELP1-TEX10-WDR18 is required for the maturation and nucleolar release of the large ribosomal subunit.
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仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Involved in Processing ITS2 3 homolog; WD repeat-containing protein 18
基因别名: Ipi3; R32184_1; WDR18
UniProt ID: (Human) Q9BV38, (Rat) Q499N3
Entrez Gene ID: (Human) 57418, (Rat) 314617