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WDR61 Antibody (PA5-30833) in ICC/IF
WDR61 Polyclonal Antibody detects WDR61 protein at cytoplasm by immunofluorescent analysis. Sample: HeLa cells were fixed in ice-cold MeOH for 5 min. Green: WDR61 protein stained by WDR61 Polyclonal Antibody (Product # PA5-30833) diluted at 1:500. Blue: Hoechst 33342 staining.
产品信息
PA5-30833
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fragment corresponding to a region within amino acids 1 and 240 of Human WDR61
偶联物
形式
Liquid
浓度
0.6 mg/mL
纯化类型
Antigen affinity chromatography
保存液
0.1M tris glycine, pH 7, with 20% glycerol
内含物
0.01% thimerosal
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2548307
产品详细信息
Recommended positive controls: HepG2, mouse stomach.
Predicted reactivity: Mouse (98%), Rat (97%), Zebrafish (90%), Xenopus laevis (89%), Chicken (94%), Rhesus Monkey (100%), Bovine (99%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
靶标信息
SKI8 is a component of the PAF and SKI complex which is composed of SKI2, SKI3 and SKI8. These are involved in transcriptional regulation and events downstream of RNA synthesis. Interaction of the SKI complex with SKI7 links the SKI complex to the exosome in order to perform mRNA degradation.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: meiotic recombination protein REC14; Meiotic recombination REC14 protein homolog; recombination protein REC14; Ski8; SKI8 homolog; Superkiller complex protein 8; WD repeat-containing protein 61
基因别名: 2700038L12Rik; 2810418I05Rik; REC14; SKI8; SKIC8; WDR61
UniProt ID: (Human) Q9GZS3, (Mouse) Q9ERF3
Entrez Gene ID: (Human) 80349, (Mouse) 66317
transcription, DNA-templated
Wnt signaling pathway
positive regulation of transcription elongation from RNA polymerase II promoter
negative regulation of myeloid cell differentiation
positive regulation of transcription from RNA polymerase II promoter
positive regulation of histone H3-K4 methylation
histone H3-K4 trimethylation
positive regulation of histone H3-K79 methylation
regulation of transcription, DNA-templated
positive regulation of histone methylation
nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5'
