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The yeast nucleolar protein NOP7 is necessary for the maturation of 66S preribosomes and interacts with numerous other proteins. One such protein is an essential, conserved WD repeat protein, NOP seven-associated protein 1 (NSA1), that is also required for the yeast 66S ribosome assembly. NSA1 is also associated with the AAA ATPase Rix7, and release of NSA1 from a novel late nucleolar pre-60S requires the Rix7 function. NSA1 has also been found upregulated in mammalian cancer cells, suggesting it may also play a role in cell proliferation.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: NOP seven-associated protein 1; WD repeat-containing protein 74
基因别名: 5730436H21Rik; AA407588; NSA1; WDR74
UniProt ID: (Human) Q6RFH5, (Mouse) Q8VCG3
Entrez Gene ID: (Dog) 483778, (Human) 54663, (Rat) 690229, (Mouse) 107071