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产品信息
PA5-17152
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide corresponding to amino acids surrounding Ser225 of human MEP50
偶联物
形式
Liquid
纯化类型
Antigen affinity chromatography
保存液
0.01M HEPES, pH 7.5, with 0.15M NaCl, 100µg/mL BSA, 50% glycerol
内含物
no preservative
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_10984370
产品详细信息
It is not recommended to aliquot this antibody.
靶标信息
WDR77 is a component of the 20S PRMT5-containing methyltransferase complex, which modifies specific arginines to dimethylarginines in several spliceosomal Sm proteins. This modification targets Sm proteins to the survival of motor neurons (SMN) complex for assembly into small nuclear ribonucleoprotein core particles.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Androgen receptor cofactor p44; MEP-50; Methylosome protein 50; MGC2722; OTTHUMP00000013473; p44/Mep50; RP11-552M11.3; testis tissue sperm-binding protein Li 44a; WD repeat-containing protein 77
基因别名: HKMT1069; MEP-50; MEP50; Nbla10071; p44; p44/Mep50; WD45; WDR77
UniProt ID: (Human) Q9BQA1
Entrez Gene ID: (Human) 79084
spliceosomal snRNP assembly
regulation of transcription from RNA polymerase II promoter
positive regulation of cell proliferation
peptidyl-arginine N-methylation
secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development
negative regulation of epithelial cell proliferation involved in prostate gland development
