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产品信息
PA5-30811
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fragment corresponding to a region within amino acids 93 and 342 of Human WDR77
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
0.1M tris glycine, pH 7, with 20% glycerol
内含物
0.01% thimerosal
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2548285
产品详细信息
Recommended positive controls: NT2D1, IMR32, U87-MG, MCF-7.
Predicted reactivity: Mouse (87%), Rat (87%), Rhesus Monkey (97%), Chimpanzee (99%), Bovine (89%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
靶标信息
WDR77 is a component of the 20S PRMT5-containing methyltransferase complex, which modifies specific arginines to dimethylarginines in several spliceosomal Sm proteins. This modification targets Sm proteins to the survival of motor neurons (SMN) complex for assembly into small nuclear ribonucleoprotein core particles.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Androgen receptor cofactor p44; MEP-50; Methylosome protein 50; Methylosome protein WDR77; MGC2722; OTTHUMP00000013473; p44/Mep50; RP11-552M11.3; testis tissue sperm-binding protein Li 44a; WD repeat-containing protein 77
基因别名: HKMT1069; MEP-50; MEP50; Nbla10071; p44; p44/Mep50; WD45; WDR77
UniProt ID: (Human) Q9BQA1
Entrez Gene ID: (Human) 79084
spliceosomal snRNP assembly
regulation of transcription from RNA polymerase II promoter
positive regulation of cell proliferation
peptidyl-arginine N-methylation
secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development
negative regulation of epithelial cell proliferation involved in prostate gland development
