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产品信息
PA5-82844
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant protein corresponding to Human WIZ. Recombinant protein control fragment (Product #RP-104572).
偶联物
形式
Liquid
浓度
0.20 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2790000
产品详细信息
Immunogen sequence: LKKKSKPCLI KKEPPAGDLA PALAEDGPPT VAPGPVQSPL PLSPLAGRPG KPGAGPAQVP RELSLTPITG AKPSATGYLG SVAAKRPLQE DRLLPAEVKA KTYIQTELPF KAKTLHEKTS HSS
靶标信息
WIZ, also known as ZNF803, was initially identified in a mouse cerebellum cDNA library screen and its message was found to be expressed in the granule cell layers of the cerebellum as well as in the dentate gyrus and olfactory bulb. Later analysis indicates however that WIZ is ubiquitously expressed. WIZ is a nuclear protein that co-localizes with G9a, a histone methyltransferase responsible for mono- and dimethylation of H3K9 at euchromatic regions. WIZ can also associate with CtBP family proteins, known to be transcriptional co-repressors, and has been suggested to link G9a/GLP complexes to the CtBP co-repressor machinery, possibly regulating complex stability and gene silencing.
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生物信息学
蛋白别名: Protein Wiz; widely-interspaced zinc finger motifs; Widely-interspaced zinc finger-containing protein; WIZ zinc finger; Zinc finger protein 803
基因别名: WIZ; ZNF803
UniProt ID: (Human) O95785
Entrez Gene ID: (Human) 58525
