Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
产品信息
PA5-67465
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
偶联物
形式
Liquid
浓度
0.1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2664670
产品详细信息
Immunogen sequence: SSQPSVAYSSN QTMGSQMVSN IPQAEVNVPG QIYSSQQLVG HYQQVSGLQK HSKLTQPQIL PLVQGQSTVL PVHVLGPTVV SQPQVSPLTV QKV
Highest antigen sequence identity to the following orthologs - mouse 59%, rat 41%.
靶标信息
WNK3 is a serine/threonine kinase involved in signal transduction and cellular communication. Members of the 'with no lysine' kinase family, such as WNK3, are serine-threonine protein kinases that lack the almost invariant catalytic lysine in subdomain II, which is important for binding ATP in the catalytic site. Instead, these kinases have a conserved lysine in subdomain I that is thought to provide this function.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
篇参考文献 (0)
您是否在文献中引用过该产品？请点击下方按钮邮件告知我们。
生物信息学
蛋白别名: PRKWNK 3; Protein kinase lysine-deficient 3; Protein kinase with no lysine 3; Serine/threonine-protein kinase WNK3; WNK 3
基因别名: KIAA1566; PRKWNK3; WNK3
UniProt ID: (Human) Q9BYP7
Entrez Gene ID: (Human) 65267
protein phosphorylation
positive regulation of sodium ion transport
positive regulation of peptidyl-threonine phosphorylation
positive regulation of ion transmembrane transporter activity
intracellular signal transduction
negative regulation of apoptotic process
protein autophosphorylation
positive regulation of calcium ion transport
positive regulation of establishment of protein localization to plasma membrane
negative regulation of pancreatic juice secretion
regulation of ion homeostasis
positive regulation of sodium ion transmembrane transporter activity
positive regulation of rubidium ion transport
positive regulation of rubidium ion transmembrane transporter activity
