Abnova

WNK4 Monoclonal Antibody (1E6)

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WNK4 Antibody (H00065266-M02) in ELISA

Detection limit for recombinant GST tagged WNK4 is 0.03 ng/mL as a capture antibody.

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产品信息

H00065266-M02

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1-5 µg/mL

酶联免疫吸附实验 (ELISA)

10 µg/mL

产品规格

种属反应

Human

宿主/亚型

Mouse / IgG1, kappa

分类

Monoclonal

类型

Antibody

克隆号

1E6

抗原

WNK4 (NP_115763.2, 1144 a.a. approximately 1243 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

1 mg/mL

纯化类型

Protein A

保存液

PBS, pH 7.4

内含物

no preservative

保存条件

-20° C, Avoid Freeze/Thaw Cycles

运输条件

Ambient (domestic); Wet ice (international)

产品详细信息

Product may be used with Sandwich ELISA (Recombinant protein).

Immunogen sequence: KHLSEVETLQ TLQKKEIEDL YSRLGKQPPP GIVAPAAMLS SRQRRLSKGS FPTSRRNSLQ RSEPPGPGIM RRNSLSGSST GSQEQRASKG VTFAGDVGRM

靶标信息

This gene encodes a member of the WNK family of serine-threonine protein kinases. The kinase is part of the tight junction complex in kidney cells, and regulates the balance between NaCl reabsorption and K(+) secretion. The kinase regulates the activities of several types of ion channels, cotransporters, and exchangers involved in electrolyte flux in epithelial cells. Mutations in this gene result in pseudohypoaldosteronism type IIB.

仅用于科研。不用于诊断过程。未经明确授权不得转售。