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产品信息
PA5-34313
产品规格
种属反应
Bovine,
Dog,
Hamster,
Human,
Mouse,
Non-human primate,
Rabbit,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic 18 amino acid peptide from internal region of human WNT10A.
偶联物
形式
Liquid
纯化类型
Antigen affinity chromatography
保存液
PBS
内含物
0.1% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2551665
产品详细信息
Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset, Mouse, Rat, Hamster, Panda, Bovine, Dog, Rabbit (100%) Elephant, Bat (94%).
靶标信息
The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It is strongly expressed in the cell lines of promyelocytic leukemia and Burkitt's lymphoma. In addition, it and another family member, the WNT6 gene, are strongly coexpressed in colorectal cancer cell lines. The gene overexpression may play key roles in carcinogenesis through activation of the WNT-beta-catenin-TCF signaling pathway. This gene and the WNT6 gene are clustered in the chromosome 2q35 region.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Protein Wnt-10a; wingless related MMTV integration site 10a; wingless-type MMTV integration site family member 10A; wingless-type MMTV integration site family, member 10A
基因别名: I79_015320; OODD; SSPS; STHAG4; WNT10A
UniProt ID: (Human) Q9GZT5, (Mouse) P70701
Entrez Gene ID: (Dog) 488528, (Rabbit) 100352839, (Bovine) 537330, (Human) 80326, (Mouse) 22409, (Chinese hamster) 100770174, (Rat) 316527
hair follicle development
positive regulation of gene expression
neural crest cell differentiation
Wnt signaling pathway
neuron differentiation
hair follicle morphogenesis
odontogenesis
regulation of odontogenesis of dentin-containing tooth
tongue development
skin development
cell fate commitment
epidermis morphogenesis
sebaceous gland development
cellular response to transforming growth factor beta stimulus
signal transduction
cell-cell signaling
multicellular organism development
organ morphogenesis
biological_process
