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产品信息
PA5-20530
产品规格
种属反应
Human,
Mouse,
Rat
已发表种属
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A 15 amino acid peptide from near the center of human Wnt10b.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS
内含物
0.02% sodium azide
保存条件
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_11152215
产品详细信息
A suggested positive control is human skeletal muscle tissue lysate.
PA5-20530 can be used with blocking peptide PEP-0650.
靶标信息
The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It may be involved in breast cancer, and its protein signaling is likely a molecular switch that governs adipogenesis. This protein is 96% identical to the mouse Wnt10b protein at the amino acid level. This gene is clustered with another family member, WNT1, in the chromosome 12q13 region.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: Protein Wnt-10b; Protein Wnt-12; wingless related MMTV integration site 10b; wingless-type MMTV integration site family member 10B; wingless-type MMTV integration site family, member 10B; WNT-10B protein; wnt-12
基因别名: SHFM6; Wnt-10b; WNT-12; Wnt10; WNT10B; WNT12
UniProt ID: (Human) O00744, (Mouse) P70702
Entrez Gene ID: (Human) 7480, (Rat) 315294, (Mouse) 22410
G2/M transition of mitotic cell cycle
negative regulation of transcription from RNA polymerase II promoter
chondrocyte differentiation
regulation of transcription from RNA polymerase II promoter
lipid metabolic process
cell cycle arrest
smoothened signaling pathway
positive regulation of cell proliferation
positive regulation of G2/M transition of mitotic cell cycle
myoblast differentiation involved in skeletal muscle regeneration
Wnt signaling pathway
neuron differentiation
positive regulation of bone mineralization
positive regulation of epithelial cell differentiation
regulation of proteasomal ubiquitin-dependent protein catabolic process
positive regulation of apoptotic process
skeletal muscle tissue regeneration
cell fate commitment
regulation of fat cell differentiation
negative regulation of fat cell differentiation
positive regulation of osteoblast differentiation
positive regulation of ossification
positive regulation of RNA polymerase II transcriptional preinitiation complex assembly
positive regulation of transcription from RNA polymerase II promoter
regulation of skeletal muscle tissue development
skeletal muscle fiber development
negative regulation of epithelial cell proliferation
protein stabilization
sensory perception of taste
positive regulation of sequence-specific DNA binding transcription factor activity
regulation of protein metabolic process
positive regulation of anagen
canonical Wnt signaling pathway
bone trabecula formation
fungiform papilla development
cellular response to organic substance
cellular response to cAMP
cellular response to parathyroid hormone stimulus
cellular response to organic cyclic compound
hematopoietic stem cell proliferation
cellular response to hydrostatic pressure
positive regulation of canonical Wnt signaling pathway
signal transduction
cell-cell signaling
multicellular organism development
organ morphogenesis
cellular response to retinoic acid
