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产品信息
PA5-18516
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
已发表种属
Mouse
宿主/亚型
Goat
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide sequence (CGRGHNTRTEKRKEK) corresponding to the internal amino acids of WNT3 (aa 315-330).
偶联物
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Ammonium sulfate precipitation
保存液
TBS, pH 7.3, with 0.5% BSA
内含物
0.02% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
AB_10979520
产品详细信息
This antibody is predicted to react with canine and rat based on sequence homology.
This antibody is tested in Peptide ELISA: antibody detection limit dilution 16,000.
靶标信息
WNT3, part of the WNT gene family, consists of structurally related genes that encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. Study of its expression in the teratocarcinoma cell line NT2 suggests that it may be implicated in the early process of neuronal differentiation of NT2 cells induced by retinoic acid. This gene is clustered with WNT3, another family member, in the chromosome 17q21 region.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: MGC131950; MGC138321; MGC138323; Proto-oncogene Int-4 homolog; Proto-oncogene Wnt-3; wingless-type MMTV integration site family member 3; wingless-type MMTV integration site family, member 3; WNT-3 proto-oncogene protein
基因别名: INT4; TETAMS; WNT3
UniProt ID: (Human) P56703
Entrez Gene ID: (Human) 7473
cell morphogenesis
mesoderm formation
gamete generation
axon guidance
anterior/posterior axis specification
dorsal/ventral axis specification
positive regulation of gene expression
Wnt signaling pathway
positive regulation of Wnt signaling pathway
neuron differentiation
embryonic forelimb morphogenesis
embryonic hindlimb morphogenesis
canonical Wnt signaling pathway involved in mesenchymal stem cell differentiation
canonical Wnt signaling pathway involved in osteoblast differentiation
cell fate commitment
positive regulation of collateral sprouting in absence of injury
negative regulation of axon extension involved in axon guidance
Spemann organizer formation at the anterior end of the primitive streak
canonical Wnt signaling pathway
limb bud formation
head morphogenesis
mammary gland epithelium development
cellular response to retinoic acid
