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产品信息
PA5-34331
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic 14 amino acid peptide from internal region of human WNT8A.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS
内含物
0.1% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2551683
产品详细信息
Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon (100%) Monkey (93%) Bat, Dog, Bovine, Horse, Rabbit (86%).
靶标信息
WNT8A, part of the WNT gene family, consists of structurally related genes that encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. Study of its expression in the teratocarcinoma cell line NT2 suggests that it may be implicated in the early process of neuronal differentiation of NT2 cells induced by retinoic acid. This gene is clustered with WNT3, another family member, in the chromosome 17q21 region.
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生物信息学
蛋白别名: Protein Wnt-8a; Protein Wnt-8d; wingless-type MMTV integration site family member 8A; wingless-type MMTV integration site family, member 8A; WNT8d
基因别名: WNT8A; WNT8D
UniProt ID: (Human) Q9H1J5
Entrez Gene ID: (Human) 7478
neural crest cell fate commitment
Wnt signaling pathway
neuron differentiation
response to retinoic acid
regulation of transcription involved in anterior/posterior axis specification
canonical Wnt signaling pathway involved in neural crest cell differentiation
palate development
canonical Wnt signaling pathway
canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment
beta-catenin destruction complex disassembly
